Effects of Topical Anesthetics on Fertility and Pregnancy: What You Need to Know - Urology

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Effects of Local Anesthetics


Hello Doctor: I have a problem with premature ejaculation, and my doctor informed me that I could apply EMLA cream (a local anesthetic) before intercourse to improve the situation.
However, I still plan to conceive.
I would like to ask: 1.
Does this medication have any effects on the fetus or affect sperm motility, making it harder to conceive? 2.
If there is an effect, would washing it off before intercourse still pose a risk? (For example, even if the surface skin is cleaned, could the medication that has absorbed into the penis still affect the sperm?)

A Cao, 40~49 year old female. Ask Date: 2006/09/18

Dr. Zhang Chengye reply Urology


Hello: 1.
The use of medication will definitely have side effects.
2.
It should not have an impact.
3.
I recommend that you consider using the stop-start technique to train for premature ejaculation issues.
Please visit the urology outpatient clinic for further diagnosis and consultation.
Thank you!

Reply Date: 2006/09/18

More Info


When considering the effects of topical anesthetics like EMLA cream on fertility and pregnancy, it is essential to understand both the pharmacological properties of the drug and the physiological processes involved in conception and fetal development.

1. Impact on Fertility: EMLA cream contains lidocaine and prilocaine, both of which are local anesthetics. These medications work by blocking nerve signals in the area where they are applied. There is limited research specifically addressing the effects of EMLA on sperm motility or overall fertility in men. However, the general consensus in the medical community is that the application of topical anesthetics is unlikely to have a significant impact on sperm function or fertility when used as directed. The primary concern would be if the anesthetic were to be absorbed systemically in significant amounts, which is unlikely with topical application, especially when used in small quantities and washed off before intercourse.

2. Effects on the Fetus: Regarding the potential effects on a developing fetus, topical anesthetics like EMLA are generally considered safe for use during pregnancy when applied in small amounts and for short durations. The systemic absorption of lidocaine and prilocaine from topical application is minimal, which reduces the risk of adverse effects on fetal development. However, it is always advisable to consult with a healthcare provider before using any medication during pregnancy, including topical anesthetics.

3. Washing Off the Anesthetic: If you apply EMLA cream and then wash it off before engaging in intercourse, the likelihood of any residual anesthetic affecting sperm motility or the fertilization process is minimal. The skin's surface would be cleansed of the cream, and while some absorption may occur, it is unlikely to reach levels that would significantly impact sperm function. The primary concern would be ensuring that the area is thoroughly cleaned to avoid any potential irritation or adverse reactions during intercourse.

4. General Recommendations: If you are planning to conceive, it is wise to minimize the use of any medications, including topical anesthetics, unless necessary. If you have concerns about premature ejaculation or other sexual health issues, discussing alternative treatment options with your healthcare provider may be beneficial. They can provide guidance on safe practices and potential therapies that do not involve medications that could raise concerns about fertility or pregnancy.

In summary, while EMLA cream is generally considered safe for use in the context of fertility and pregnancy, it is always best to consult with your healthcare provider for personalized advice. They can help you weigh the risks and benefits based on your specific circumstances and health history.

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