Can High Doses of Vitamin C Help Treat Urticaria Symptoms? - Dermatology

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Some people say that urticaria requires a large intake of vitamin C?


I have been experiencing hives for about half a month.
In addition to the rash, I feel a tightness and discomfort in my chest, and my voice has become hoarse.
I am currently taking medication (levocetirizine and Clarinase twice a day), but I still experience outbreaks daily.
I have had blood tests done, but the results are not yet available.
Someone from Amway suggested that I need to take a large amount of vitamin C and B vitamins, specifically the equivalent of 12 oranges a day, and that my diet should consist of natural foods to boost my immune system and improve my allergy symptoms.
I am wondering if this approach is effective and if taking large amounts of vitamin C is advisable.
Can you please advise me on this method?

dong-m, 40~49 year old female. Ask Date: 2006/10/13

Dr. Jiang Yujiao reply Dermatology


Hello: In response to your question, the occurrence of urticaria is considered an allergic reaction of the body and is not necessarily caused by a weakened immune system.
If you experience tightness in the chest during an outbreak, it indicates edema of the mucous membranes, which can lead to respiratory difficulties in severe cases.
It is safer to take medication regularly.
The causes of allergies vary from person to person and can be quite diverse.
Some individuals may be allergic to citrus fruits, while others may react to artificial colorants or tablet formulations.
Therefore, any food or vitamin could potentially trigger an allergic reaction.
Please consult a nearby dermatologist for further evaluation.

Reply Date: 2006/10/13

More Info


High doses of Vitamin C have been a topic of interest in the treatment of various conditions, including allergic reactions such as urticaria (hives). Urticaria is characterized by the sudden appearance of itchy welts on the skin, which can be triggered by a variety of factors, including allergens, stress, and certain medications. In your case, it seems that despite taking medications like levocetirizine and Clarinase, you are still experiencing symptoms.
Vitamin C, or ascorbic acid, is known for its antioxidant properties and its role in immune function. Some studies suggest that Vitamin C may help reduce the severity of allergic reactions and improve overall immune response. The rationale behind using high doses of Vitamin C in treating urticaria is based on its potential to stabilize mast cells, which release histamine and other chemicals during allergic reactions. By stabilizing these cells, Vitamin C may help reduce the frequency and severity of urticaria outbreaks.

However, the recommendation to consume an excessive amount of Vitamin C—such as the equivalent of 12 oranges a day—should be approached with caution. While Vitamin C is water-soluble and excess amounts are typically excreted through urine, extremely high doses can lead to gastrointestinal disturbances, including diarrhea, nausea, and abdominal cramps. Furthermore, there is limited scientific evidence supporting the effectiveness of such high doses specifically for urticaria treatment.

In addition to Vitamin C, B vitamins play a crucial role in maintaining overall health, including skin health and immune function. However, the idea that taking large amounts of B vitamins will directly alleviate urticaria symptoms is not well-supported by clinical evidence. It is essential to maintain a balanced diet rich in fruits, vegetables, whole grains, and lean proteins to ensure adequate intake of all necessary vitamins and minerals.

If you are considering increasing your Vitamin C intake significantly, it is advisable to consult with a healthcare professional first. They can provide personalized recommendations based on your health history and current medications. It is also important to monitor your symptoms closely and report any changes to your doctor, especially if you are experiencing difficulty breathing or persistent tightness in your chest, as these could indicate a more severe allergic reaction.

In summary, while high doses of Vitamin C may offer some benefits for immune support and potentially reduce allergic reactions, the approach should be cautious and guided by a healthcare professional. It is crucial to address the underlying causes of urticaria and explore other treatment options if current medications are not providing relief. Always prioritize a balanced diet and consult with your doctor before making significant changes to your supplement regimen.

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