Taking contraceptive pills without knowing you are pregnant?
I unknowingly took the contraceptive pill Neovlar and Domperidone while pregnant.
I found that the ingredients in Neovlar are Ethinylestradiol 50 μg and Levonorgestrel 0.25 mg.
My last menstrual period started on August 28, and I took the medication from September 20 to October 4 for a total of 15 days.
I am concerned about whether this could affect the fetus.
Additionally, please help me check the pregnancy category of the above ingredients.
If possible, please provide a website for checking pregnancy medication categories for future reference.
Miss Monther, 20~29 year old female. Ask Date: 2006/10/29
Dr. Hou Fangmin reply Pharmacology
Hello: Every prospective mother should be very cautious about the medications she takes, which is a good practice.
Medications during pregnancy are classified into five categories.
Below are the classifications for medications used by pregnant women:
- Category A: No evidence of risk in the first trimester of pregnancy.
- Category B: Animal studies show no harm, but there is a lack of sufficient data in pregnant women.
- Category C: Animal studies indicate harm, but there is a lack of well-controlled studies in pregnant women.
- Category D: There is evidence of risk to the human fetus, but the medication may be used in life-threatening situations.
- Category X: There is evidence of risk to the human fetus, and the risks clearly outweigh the benefits.
This category is absolutely contraindicated for pregnant women.
Nolvar is classified as Category X, while Domperidone is classified as Category C.
Your last menstrual period was on August 28, and you were taking medication during the 6th and 7th weeks of pregnancy, which is generally not advisable, as it is recommended to stop taking contraceptives for three months before trying to conceive.
You should consult with your obstetrician, and it is essential to have an ultrasound and maternal blood tests.
You can visit the pharmacy department at National Taiwan University Hospital or check the pregnancy medication classification website.
It is understandable that you are feeling anxious; remember to see your obstetrician as soon as possible.
Wishing you a safe and happy journey to motherhood!
Reply Date: 2006/10/29
More Info
Taking birth control pills during an unknown pregnancy can be a concerning situation for many women. In your case, you mentioned taking Neovlar, which contains Ethinylestradiol and Levonorgestrel, along with Domperidone, from September 20 to October 4, while your last menstrual period started on August 28. This means that you may have been unknowingly pregnant during this time.
First, it's important to understand the potential effects of these medications on a developing fetus. Ethinylestradiol and Levonorgestrel are both synthetic hormones used in many combined oral contraceptives. While there is limited data on the effects of these specific medications when taken during early pregnancy, studies have shown that exposure to hormonal contraceptives in the first trimester does not significantly increase the risk of major congenital malformations. However, there is still some uncertainty, and the potential risks may vary depending on the timing and dosage of exposure.
Domperidone is primarily used to treat nausea and vomiting. It is classified as a Category C medication by the FDA, which means that risk cannot be ruled out. Animal studies have shown adverse effects, but there are no adequate and well-controlled studies in pregnant women. Therefore, it should be used during pregnancy only if the potential benefits justify the potential risks to the fetus.
Regarding the classification of the medications you mentioned, the FDA categorizes drugs based on their safety during pregnancy as follows:
- Category A: Controlled studies show no risk.
- Category B: No evidence of risk in humans; animal studies may show risk, but human studies do not.
- Category C: Risk cannot be ruled out; either animal studies have shown an adverse effect, or there are no adequate studies in humans.
- Category D: Positive evidence of risk; the benefits may outweigh the risks in certain situations.
- Category X: Contraindicated in pregnancy; studies in animals or humans have demonstrated fetal abnormalities.
For Neovlar, the components Ethinylestradiol and Levonorgestrel are generally considered to fall under Category X when used for contraception, meaning they should not be used during pregnancy. However, the actual risk to the fetus from short-term exposure during the early weeks of pregnancy is still a subject of ongoing research.
If you are concerned about the potential effects of these medications on your pregnancy, it is crucial to consult with a healthcare provider. They can provide personalized advice based on your specific situation and may recommend additional monitoring or testing to ensure the health of both you and your baby.
For future reference, you can check the FDA's pregnancy categories and drug safety information on their official website or through resources like the American College of Obstetricians and Gynecologists (ACOG) and the National Institutes of Health (NIH). These resources can provide valuable information regarding the safety of medications during pregnancy.
In conclusion, while there may be some risks associated with taking birth control pills and Domperidone during an unknown pregnancy, the actual impact on fetal development can vary. It is essential to have open communication with your healthcare provider to address any concerns and ensure the best possible outcome for your pregnancy.
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