Chickenpox Antibodies: What Your Test Results Mean for Pregnancy

Q: Chickenpox Antibodies: What Your Test Results Mean for Pregnancy

Dear readers： <br>1. <br>First, ask yourself or your family members if you have ever had chickenpox. <br>If you have had it, there is no need to worry about transmitting it to the newborn during the perinatal period. <br>If you have not had it, it indicates that you have recently

Varicella antibodies

I had a varicella antibody test: CHICKEN POX IgG, with a result of 1175.
The normal reference value is (-)<200 mIU/ml.
The lab technician said I have antibodies, but I want to confirm whether I truly have antibodies because I am planning to get pregnant.

Ms. Chen, 20~29 year old female. Ask Date: 2006/11/23

Dr. Liao Zhongxin reply Internal Medicine

Dear readers:
1.
First, ask yourself or your family members if you have ever had chickenpox.
If you have had it, there is no need to worry about transmitting it to the newborn during the perinatal period.
If you have not had it, it indicates that you have recently received the chickenpox vaccine and have sufficient antibodies.

2.
Generally, IgG indicates past or recent infection or vaccination, while IgM indicates a recent infection.

3.
During pregnancy, the concern should be whether there is a risk of chickenpox infection during the perinatal period, which refers to the time from one month before delivery to one week after delivery.
If there are no antibodies, consider receiving the vaccine and immunoglobulin.
You may want to consult with an obstetrician, pediatrician, or infectious disease specialist for further discussion.
Thank you!

Reply Date: 2006/11/23

More Info

When it comes to understanding your chickenpox (varicella) antibody test results, it's important to interpret them in the context of your pregnancy plans. Your test result shows a value of 1175 mIU/ml for the Chickenpox IgG antibody, which is significantly above the normal standard value of less than 200 mIU/ml. This indicates that you have a high level of IgG antibodies against the varicella virus, suggesting that you have either had a previous infection or have been vaccinated against chickenpox.

In terms of pregnancy, having these antibodies is beneficial. Women who are immune to chickenpox are at a lower risk of contracting the virus during pregnancy, which can lead to serious complications for both the mother and the fetus. If a pregnant woman contracts chickenpox, especially in the first or second trimester, it can lead to congenital varicella syndrome, which can cause severe birth defects, including limb abnormalities, skin scarring, and neurological issues. Additionally, if a mother develops chickenpox shortly before or after delivery, the newborn may be at risk for severe varicella infection.

Since your test indicates that you have protective antibodies, you are considered immune to chickenpox, which is a positive factor as you prepare for pregnancy. This immunity will help protect you and your future baby from the risks associated with chickenpox infection during pregnancy.

It is also important to note that if you are planning to conceive, you should ensure that all other vaccinations are up to date and discuss any concerns with your healthcare provider. They can provide personalized advice based on your medical history and current health status.
In summary, your high IgG level indicates that you are immune to chickenpox, which is advantageous as you prepare for pregnancy. This immunity will help mitigate the risks associated with chickenpox during this critical time. Always consult with your healthcare provider for tailored advice and to address any further questions you may have regarding your health and pregnancy planning.

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