Low Platelet Count: Causes, Treatments, and Concerns - Internal Medicine

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A low platelet count, confirmed by bone marrow examination, indicates a viral infection?


Hello Doctor: On December 27, 2006, I visited a dermatologist due to purple spots and some bruising on my body.
The doctor suggested that I go to the hospital for a blood test, suspecting that my platelet count was too low.
The test results showed a platelet count of only 8,000.
The doctor was very concerned and immediately administered a platelet transfusion.
However, upon retesting, my platelet count decreased to 4,000.
Consequently, the doctor performed a bone marrow biopsy because he was worried about the possibility of hemophilia or systemic lupus erythematosus.
The results ruled out both conditions and indicated that it was a viral infection triggered by a cold.
During this time, I took corticosteroids and gastric medication prescribed by the doctor and stayed in the hospital for six days.
Upon discharge, my platelet count had risen to 65,000.
After returning home and continuing the medication, I went for a follow-up appointment a week later, and my platelet count was only 51,000.
The doctor continued to prescribe the same medication and asked me to return for a follow-up in two weeks.
I would like to ask: 1.
After discharge, I got my period.
Could this condition affect my platelet count? 2.
Besides medication, are there any dietary treatments for low platelet counts? 3.
Since my bone marrow biopsy, I have been experiencing lower back pain.
Is this normal? 4.
Why have the purple spots on my body disappeared, yet my platelet count has not significantly increased? I apologize for these concerns, as they are causing me a lot of anxiety, so I am seeking your advice! Thank you very much.

Joan, 10~19 year old female. Ask Date: 2007/01/10

Dr. Liao Zhongxin reply Internal Medicine


Dear readers,
1.
Regarding the low platelet count and accompanying purpura and bruising observed on December 27, 1995, common causes include liver dysfunction (cirrhosis), kidney dysfunction (dialysis), infections (viral infections, such as upper respiratory infections), hematological disorders (bone marrow failure, leukemia), and autoimmune diseases (systemic lupus erythematosus).
Based on your description, it seems that platelet transfusion could correct the issue, and it leans more towards a viral infection.
With time, recovery can be achieved through medications (steroids) and dietary sources (pig blood, organ meats, dark green vegetables).
If the platelet count remains persistently below 20,000 to 50,000 after two to three months, it is advisable to seek a detailed examination at a medical facility with a hematology-oncology specialist.
2.
Light menstrual flow does not affect platelet counts; however, if the flow is heavy and prolonged, it is important to consult a gynecologist to determine the underlying cause for appropriate treatment.
3.
Prior to a bone marrow aspiration, local disinfection is performed, and after administering a local anesthetic for pain relief, a collection device with a diameter of approximately 1 cm is used to obtain bone marrow tissue.
The procedure may inevitably cause some injury, nerve damage, and bleeding as side effects, which should resolve within 1 to 2 weeks.
By Dr.
Liao Chongxin

Reply Date: 2007/01/10

More Info


Low platelet count, or thrombocytopenia, can be a concerning condition, especially when it manifests with symptoms such as easy bruising or the appearance of petechiae (small purple spots on the skin). Your experience of having a platelet count as low as 8,000 is indeed alarming, and it is understandable that you have many questions regarding your condition and its implications.

1. Menstrual Cycle and Platelet Count: It is possible that your menstrual cycle can influence your platelet count. During menstruation, there can be a natural decrease in platelet levels due to the loss of blood. Additionally, if you have any underlying conditions that affect your platelet production or survival, menstruation could exacerbate these issues. However, the degree of impact varies from person to person.

2. Dietary Considerations: While medications are a primary treatment for low platelet counts, certain dietary choices may support overall blood health. Foods rich in vitamin K (such as leafy greens), vitamin B12 (found in meats, eggs, and dairy), and folate (found in beans, peas, and fortified grains) can be beneficial. Additionally, staying well-hydrated and consuming foods high in antioxidants (like fruits and vegetables) may help your body recover. However, it is crucial to consult with your healthcare provider before making significant dietary changes, especially if you are on medication.

3. Post-Bone Marrow Aspiration Discomfort: Experiencing some discomfort or soreness in the lower back after a bone marrow aspiration is not uncommon. The procedure can cause temporary pain or discomfort at the site of the aspiration, and this can radiate to the surrounding areas. If the pain persists or worsens, it is advisable to follow up with your healthcare provider.

4. Disappearance of Bruises and Platelet Levels: The resolution of bruises does not always correlate directly with an increase in platelet count. Bruises can heal as the underlying blood vessels repair themselves, and the body may be able to manage minor bleeding episodes even with lower platelet counts. It is also possible that your body is compensating in other ways, such as through increased clotting factor activity or other mechanisms that help stabilize your condition.

Given your history of low platelet counts and the recent viral infection that was identified as a potential cause, it is essential to continue monitoring your platelet levels closely. Regular follow-ups with your healthcare provider are crucial to ensure that your condition is managed effectively. If your platelet counts do not improve or if you experience new symptoms, further evaluation may be necessary.

In summary, while low platelet counts can be concerning, understanding the underlying causes and maintaining open communication with your healthcare team can help you navigate this condition. It is important to address your concerns with your doctor, who can provide personalized advice and treatment options based on your specific situation.

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