Alternative Treatments and Risks of Gallstones: What You Need to Know - Surgery

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Gallstones


1.
Besides laparoscopic cholecystectomy, are there other treatment options for gallstones? Is it possible to use medication to dissolve or expel the stones?
2.
What are the risks associated with laparoscopic cholecystectomy? Are there any long-term complications after the surgery?
3.
If the gallbladder is not removed (not treated), are there any risks? Over the past year, I have been admitted to the emergency room six times due to severe upper abdominal pain, and I was recently diagnosed with gallstones.
I often experience bloating after overeating, and in severe cases, it leads to pain and vomiting, but my family opposes the idea of me undergoing gallbladder removal surgery.

Pingzi, 20~29 year old female. Ask Date: 2000/11/15

Dr. Qiu Shoutiao reply Surgery


ANSWER: 1.
There are no other treatment options.
Dissolution therapy is designed specifically for cholesterol-based gallstones (common in Western populations), but statistics show that once the medication is discontinued, cholesterol stones can re-form.
Dissolution therapy is "ineffective" for gallstones primarily composed of pigment in Eastern populations! 2.
Risks: a) Injury to the common bile duct b) Postoperative internal bleeding a) & b) have a probability of < 0.5% when performed by an experienced surgeon.
Postoperative sequelae: 1/3 of patients will experience diarrhea after surgery, and consuming fatty foods may lead to digestive discomfort, but these symptoms typically resolve within six months.
Even if these symptoms occur, they can be managed with medication.
3.
Based on long-term follow-up of the natural history of gallstone patients (i.e., no treatment), it is known that: (1) Asymptomatic gallstone patients—1/3 will eventually develop cholecystitis, while 2/3 remain asymptomatic.
(2) Patients who have already experienced pain due to gallstones—98% will continue to have gallstone pain.
Since you have experienced gallstone pain six times recently, you should undergo surgery as soon as possible.
Otherwise, simple gallstone pain (caused by gallstones obstructing the cystic duct) may worsen into acute cholecystitis, which cannot be treated with laparoscopic surgery and will require traditional open surgery instead! Having visited the emergency room six times, you should—must—have surgery!

Reply Date: 2000/11/15

More Info


When it comes to managing gallstones, particularly in cases like yours where there have been recurrent episodes of severe abdominal pain, it's crucial to weigh the options carefully. Let's break down your questions regarding alternative treatments, the risks associated with laparoscopic cholecystectomy (gallbladder removal), and the potential dangers of not undergoing surgery.


1. Alternative Treatments for Gallstones
Currently, the primary treatment for symptomatic gallstones is laparoscopic cholecystectomy. This minimally invasive surgery is effective in alleviating symptoms and preventing complications associated with gallstones. While there are some non-surgical options, they are limited and often not as effective.
Medications exist that can dissolve cholesterol-based gallstones, such as ursodeoxycholic acid (UDCA). However, these medications are primarily effective for cholesterol stones and may take months or even years to work. Furthermore, once the medication is stopped, there is a high chance that the stones will reform. For pigment stones, which are more common in certain populations, these medications are generally ineffective.
In summary, while there are some medications that can help dissolve gallstones, they are not a reliable long-term solution, especially for symptomatic patients. Surgery remains the most definitive treatment.


2. Risks of Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is considered a safe procedure, but like any surgery, it carries risks. The potential complications include:
- Injury to the bile duct: This is a rare but serious complication that can lead to significant morbidity.

- Bleeding: While the risk of postoperative bleeding is low (less than 0.5% in experienced hands), it can occur.

- Infection: As with any surgical procedure, there is a risk of infection at the incision sites or within the abdominal cavity.

Post-surgery, some patients may experience digestive issues, such as diarrhea or difficulty digesting fatty foods. These symptoms often improve over time, typically within six months. It's important to note that even if these symptoms occur, they can often be managed with dietary adjustments or medications.


3. Risks of Not Removing the Gallbladder
Given your history of severe abdominal pain and multiple emergency room visits, the risks of not undergoing surgery are significant.
- Progression of Symptoms: Patients with symptomatic gallstones often experience worsening symptoms over time. The likelihood of developing acute cholecystitis (inflammation of the gallbladder) is high, especially after multiple episodes of pain. Acute cholecystitis can lead to severe complications, including perforation of the gallbladder, which is a surgical emergency.

- Pancreatitis: Gallstones can also migrate and block the pancreatic duct, leading to pancreatitis, a painful and potentially life-threatening condition.

- Quality of Life: Chronic pain and digestive issues can significantly impact your quality of life, making it difficult to engage in daily activities.


Conclusion
In your case, given the recurrent nature of your symptoms and the potential for serious complications, it is advisable to have a thorough discussion with your healthcare provider about the benefits and risks of surgery. While family concerns about surgery are understandable, the risks associated with leaving symptomatic gallstones untreated can outweigh the risks of the surgery itself.
Ultimately, the decision should be made collaboratively with your healthcare team, considering your specific circumstances and health status. If surgery is recommended, choosing an experienced surgeon can further minimize risks and improve outcomes.

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