Irregular Periods and Swelling After Hormonal Treatments - Family Medicine

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Taking menstrual induction medication for six months?


About a year ago, I took emergency contraception once, which led to irregular menstrual cycles.
Over the past six months, I have taken several menstrual induction medications and even received hormonal injections, but my menstrual cycle has not returned to normal.
I usually have very regular periods, but this past half year has been completely chaotic.
Recently, I have noticed severe edema in my lower limbs.
I have heard that taking hormones can cause edema, but it has been over three weeks since I last took any hormones, and my period is about two weeks late, with another two weeks until my next expected period.
Could the edema be due to the hormonal treatment? I have always experienced discomfort with hormonal medications and am very reluctant to take them again.
Previously, when I consulted a gynecologist about regulating my menstrual cycle, the doctor suggested taking ovulation pills or contraceptives, but I have not returned for follow-up due to my unwillingness to take hormones again.
However, the severe edema in my lower limbs is causing me significant anxiety, and I am unsure if it is a side effect of the hormones or if there is an underlying issue with my body.
I feel extremely worried and would appreciate any guidance from a doctor.
Thank you very much.

Dog, 20~29 year old female. Ask Date: 2007/03/11

Dr. Zhan Deqin reply Family Medicine


Taking hormones can lead to mild edema, but there are many potential causes for edema.
A thorough examination is recommended, and it is advisable to consult a nephrologist for further evaluation.

Reply Date: 2007/03/11

More Info


Irregular menstrual cycles and swelling, particularly in the lower extremities, can be concerning symptoms, especially after hormonal treatments. It’s understandable that you are feeling anxious about these changes in your body. Let’s break down the potential causes and implications of your symptoms.

Firstly, hormonal treatments, including emergency contraceptive pills (often referred to as "morning-after pills") and other hormonal medications, can significantly impact your menstrual cycle. These medications work by altering the hormonal balance in your body, which can lead to irregularities in your menstrual cycle. It's not uncommon for individuals who have taken hormonal medications to experience changes in their cycle, including delayed periods, missed periods, or even heavier or lighter bleeding than usual.

In your case, you mentioned that you have taken emergency contraception and have also used medications to induce menstruation. The fact that your menstrual cycle was previously very regular and has now become erratic suggests that your body is still adjusting to the hormonal changes. It can take some time for your hormonal levels to stabilize after such treatments, and this could explain the irregularity you are experiencing.

Regarding the swelling in your lower extremities, it is indeed possible that hormonal treatments can lead to fluid retention, which may manifest as swelling. Hormones, particularly estrogen, can cause the body to retain water, leading to edema (swelling). However, since it has been three weeks since your last hormonal treatment, it is less likely that the swelling is directly caused by the hormones you took at that time. Other factors could be contributing to your swelling, such as dietary changes (increased salt intake), lack of physical activity, or even underlying medical conditions such as kidney or heart issues.

Given that you have been experiencing significant swelling, it is essential to consult with a healthcare provider. They can perform a thorough evaluation, including a physical examination and possibly some laboratory tests, to determine the underlying cause of your symptoms. It’s crucial to rule out any serious conditions that could be contributing to the swelling, such as venous insufficiency or other circulatory issues.

If you are hesitant to return to hormonal treatments due to previous discomfort, it’s important to communicate this with your healthcare provider. They can explore alternative options for managing your menstrual cycle and any associated symptoms. For instance, lifestyle modifications, dietary changes, or non-hormonal medications may be recommended to help regulate your cycle and manage swelling.

In summary, while hormonal treatments can lead to irregular periods and swelling, it is essential to consider other potential causes for your symptoms. Consulting with a healthcare professional is the best course of action to address your concerns and find an appropriate treatment plan that aligns with your preferences and health needs. Remember, your health and well-being are paramount, and seeking guidance from a medical professional can provide you with the reassurance and support you need during this time.

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