Male Gynecomastia: Causes and Treatment Options - Breast and Thyroid

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Gynecomastia caused by elevated prolactin levels?


Hello, doctor.
I am a 28-year-old male who has experienced persistent breast tissue development since puberty, which is quite noticeable when I wear clothes and has caused me considerable distress.
I went to the hospital for various tests (including brain imaging and blood tests).
All hormone levels, including testosterone and estrogen, were within normal ranges for males, except for prolactin, which was higher than normal.
The doctor suggested that this might be due to medication I took and advised me to return for a follow-up blood test in three months.
However, I forgot to go back for the re-evaluation due to work commitments.

Now, I have some questions:
1.
Since puberty, I have rarely taken any medication (I don't even take medicine when I have a cold).
Why is this happening?
2.
Do I need to go back to the hospital for another blood test? If so, do I need to wait another three months before testing again?
3.
Is it possible to treat this condition with medication, or is surgery necessary?
Thank you in advance.
Wishing you good health.

Carl, 20~29 year old female. Ask Date: 2007/04/06

Dr. Yang Mingqi reply Breast and Thyroid


Hello, online user: If your prolactin levels are elevated, in addition to ruling out medication factors, it is important to consider the possibility of a pituitary tumor.
I recommend that you visit the hospital for a re-evaluation of your prolactin levels.
If the values are abnormally high, you should consult a neurologist or neurosurgeon to assess the potential for a pituitary tumor.
Dr.
Yang Ming-Chi

Reply Date: 2007/04/06

More Info


Gynecomastia, characterized by the enlargement of breast tissue in males, can be a source of significant psychological distress and embarrassment. Understanding its causes and treatment options is crucial for those affected.

Causes of Gynecomastia
Gynecomastia can arise from various factors, including hormonal imbalances, medications, and underlying health conditions. In your case, the elevated prolactin levels are noteworthy. Prolactin is a hormone primarily associated with lactation, but elevated levels in men can lead to breast tissue growth. Common causes of elevated prolactin include:
1. Medications: Certain drugs, especially those affecting hormonal balance, such as anti-androgens, antidepressants, and some heart medications, can lead to increased prolactin levels.

2. Hormonal Imbalances: Conditions that disrupt the balance between testosterone and estrogen can lead to gynecomastia. Even if testosterone levels are normal, an increase in estrogen or a decrease in testosterone can cause breast tissue growth.

3. Health Conditions: Liver disease, kidney failure, hyperthyroidism, and tumors of the pituitary gland can also elevate prolactin levels and contribute to gynecomastia.


Your Specific Situation
1. Lack of Medication: You mentioned that you have not taken any medications since adolescence. This raises the question of whether there might be an underlying condition affecting your hormone levels. It’s essential to consider that even without medication, natural hormonal fluctuations or health issues could be at play.

2. Follow-Up Testing: Yes, it is advisable to return to the hospital for follow-up blood tests. Monitoring your prolactin levels and possibly other hormones can provide insight into whether the condition is persistent or if it resolves on its own. Waiting three months for a follow-up is standard practice, but if you experience any new symptoms or significant changes, you should seek medical advice sooner.

3. Treatment Options: Treatment for gynecomastia depends on the underlying cause. If the elevated prolactin is due to a medication or a treatable condition, addressing that issue may resolve the gynecomastia. Options include:
- Medications: If the gynecomastia is due to hormonal imbalances, medications like bromocriptine or cabergoline may be prescribed to lower prolactin levels. However, this should only be done under the supervision of a healthcare provider.

- Surgery: If gynecomastia persists and causes significant distress or physical discomfort, surgical options such as liposuction or mastectomy may be considered. Surgery is typically reserved for cases that do not respond to medical treatment or for patients who prefer a definitive solution.


Conclusion
In summary, gynecomastia can be a complex condition influenced by various factors. Given your elevated prolactin levels, it is crucial to follow up with your healthcare provider for further evaluation and management. They may recommend additional tests to rule out other causes and discuss potential treatment options tailored to your specific situation. Remember, you are not alone in this, and there are effective treatments available to help you manage this condition.

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