Navigating Cervical In Situ Carcinoma: Should You Consider Hysterectomy? - Obstetrics and Gynecology

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Cervical carcinoma in situ


Hello Dr.
Li, I underwent a cone biopsy on February 2nd, and the report showed no residual disease, which was very reassuring at the time.
However, during my routine Pap smear on May 1st, an abnormality was detected again, with a grade of 10, up from 9 before the surgery.
Why has it increased by one grade? The doctor used a colposcope and said he couldn't see anything abnormal, but he recommended a hysterectomy for safety.
What should I do? I feel very helpless (I have one child and do not plan to have more).
Is it absolutely necessary to have the uterus removed?

HA, 30~39 year old female. Ask Date: 2007/05/09

Dr. Li Guanghan reply Obstetrics and Gynecology


Hello: You may discuss with your physician whether they agree to perform another cervical conization.
After that, you can decide whether to preserve or remove the uterus based on the pathology report.
Online responses are for reference only, and you should follow the advice of your attending physician.
Hsinchu City Hospital, Department of Obstetrics and Gynecology.

Reply Date: 2007/05/09

More Info


Navigating the complexities of cervical in situ carcinoma, particularly when faced with the decision of whether to undergo a hysterectomy, can be daunting. Your situation, where a cone biopsy showed no residual disease but subsequent Pap smear results indicated an increase in abnormality, raises several important considerations.

Firstly, it’s essential to understand the nature of cervical intraepithelial neoplasia (CIN) and its progression. CIN is categorized into grades based on the severity of cellular abnormalities, with CIN1 being mild dysplasia, CIN2 moderate dysplasia, and CIN3 severe dysplasia, which is often referred to as high-grade squamous intraepithelial lesion (HSIL). The presence of HSIL indicates a significant risk for progression to cervical cancer if left untreated.
Your initial cone biopsy results showing no residual disease were indeed encouraging. However, the subsequent increase in the abnormality level from 9 to 10 in your Pap smear suggests that there may still be underlying issues that need to be addressed. It’s not uncommon for Pap results to fluctuate, but a persistent abnormality, especially after a previous diagnosis of CIN, warrants careful consideration.

The recommendation from your physician to consider a hysterectomy is based on the principle of ensuring complete removal of any potentially malignant tissue. Hysterectomy, particularly in cases where there is a history of high-grade lesions, is often viewed as a definitive treatment option. Given that you have expressed that you do not plan to have more children, this option may be more palatable for you.
However, before making a decision, it’s crucial to weigh the benefits and risks. A hysterectomy can provide peace of mind by eliminating the risk of cervical cancer, but it is also a significant surgical procedure with its own set of risks and potential complications. These can include infection, bleeding, and longer recovery times. Additionally, the emotional and psychological impact of such a decision should not be underestimated.

If you are uncertain about the necessity of a hysterectomy, consider seeking a second opinion from another gynecologic oncologist. They can review your case, including your biopsy results and Pap smear history, and provide additional insights. It may also be beneficial to discuss the possibility of continued surveillance versus surgical intervention. Some patients opt for a watchful waiting approach with regular Pap smears and colposcopy if they are not experiencing significant abnormalities.

In summary, while a hysterectomy may be recommended to ensure the complete removal of any potentially cancerous cells, it is essential to consider your personal circumstances, including your family planning desires and your comfort level with the procedure. Engaging in open discussions with your healthcare provider and possibly seeking a second opinion can help you make an informed decision that aligns with your health goals and personal values. Remember, you are not alone in this journey, and there are resources and support systems available to help you navigate these challenging decisions.

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