Is Numbness in Hands and Feet After Chemotherapy Normal? - Family Medicine

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Is it normal to experience numbness in the hands and feet after chemotherapy? How long does it typically last?


Hello Doctor, my father has been undergoing chemotherapy for rectal cancer.
During and after the chemotherapy, he has been experiencing persistent numbness in his hands and feet, and sometimes his extremities feel cold and uncomfortable.
His walking has also become less agile.
I would like to ask if this numbness is a normal occurrence, how long it might take to improve after the chemotherapy has ended, and if there are any specific things we should be aware of.
I apologize for any inconvenience.

meng, 30~39 year old female. Ask Date: 2007/06/05

Dr. Chen Bozhang reply Family Medicine


Hello: In response to your question, numbness and coldness in the hands and feet can be potential side effects after chemotherapy, affecting blood circulation and causing complications in the nervous system.
However, not every chemotherapy drug will cause these symptoms.
It is advisable to consult with the oncologist and inform them of these phenomena to seek control and improvement of the symptoms.

Reply Date: 2007/06/05

More Info


Numbness in the hands and feet after chemotherapy is a common side effect experienced by many patients undergoing cancer treatment. This condition, often referred to as peripheral neuropathy, can manifest as tingling, numbness, or a burning sensation in the extremities. It is particularly prevalent among patients treated with certain chemotherapy agents, such as taxanes (e.g., paclitaxel) and platinum-based drugs (e.g., cisplatin).
The mechanism behind chemotherapy-induced peripheral neuropathy (CIPN) is not entirely understood, but it is believed to involve damage to the peripheral nerves due to the neurotoxic effects of the chemotherapy drugs. This can lead to symptoms such as numbness, tingling, and even pain in the hands and feet. In some cases, patients may also experience cold sensations or a feeling of heaviness in their limbs, which can affect mobility and overall quality of life.

In your father's case, experiencing numbness and discomfort in his hands and feet after chemotherapy for rectal cancer is indeed a recognized phenomenon. The duration and severity of these symptoms can vary significantly from person to person. For some, the numbness may improve within weeks or months after the completion of chemotherapy, while others may experience persistent symptoms for a longer period.
It is essential to communicate these symptoms to your father's oncologist, as they can provide guidance on managing the side effects. There are several strategies that may help alleviate the discomfort associated with peripheral neuropathy:
1. Medication: Certain medications, such as gabapentin or pregabalin, may be prescribed to help manage neuropathic pain and discomfort.
2. Physical Therapy: Engaging in physical therapy can help improve mobility and strength, which may alleviate some of the symptoms associated with numbness.

3. Nutritional Support: Some studies suggest that certain vitamins, particularly B vitamins, may support nerve health. However, it is crucial to consult with a healthcare provider before starting any new supplements.

4. Lifestyle Modifications: Gentle exercises, such as walking or swimming, can improve circulation and may help reduce symptoms. Additionally, avoiding extreme temperatures and protecting the feet from injury is advisable.

5. Alternative Therapies: Some patients find relief through acupuncture, massage, or other complementary therapies.
As for the timeline for improvement, it is challenging to provide a specific duration, as recovery can vary widely among individuals. Some patients may notice gradual improvement over a few months, while others may take longer. Continuous follow-up with the healthcare team is essential to monitor symptoms and adjust treatment plans as necessary.

In summary, while numbness in the hands and feet after chemotherapy is a common side effect, it is crucial to address these symptoms with your father's healthcare provider. They can offer tailored advice and treatment options to help manage the discomfort and improve his quality of life. Additionally, staying informed about potential side effects and maintaining open communication with the medical team will be beneficial as your father continues his recovery journey.

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