Menstrual Irregularities: Causes, Treatments, and Concerns - Obstetrics and Gynecology

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Menstrual irregularities


Hello, doctor...
After a menstrual adjustment, my periods have been irregular for the past six years.
I now need to take medication (PROVERA) to induce menstruation.
I take it once every three months, and after each course (2-3 days of normal flow, about 3-5 pills), I have tried adjusting the dosage, but it has not been effective.
Last month, another doctor prescribed me Dydrogesterone, and after finishing it, I got my period on June 10, but it was very light, lasting only one day, followed by 2-3 days of brown discharge.
I felt bloated in my abdomen, and then I got my period again on June 27, similar to June 10, with a burning sensation in my lower abdomen and redness and pain in my genital area.
Due to the brown discharge, I couldn't assess the vaginal discharge.
After a consultation, a urine test showed signs of inflammation, and the doctor said it was cystitis.
However, I do not experience frequent urination or pain while urinating.
Could there be other issues? The doctor mentioned that my period would come in two weeks.
I would like to ask:
1.
The fact that my period did not come as expected, does it mean that something is retained in my uterus that needs to be expelled? Should I take medication to induce it, or should I follow the doctor's advice and wait for it to come naturally (since it has never come naturally before)? Or should I take medication? I am worried that since nothing has been expelled from February 20 until now, there could be pathological changes.
2.
The doctor prescribed me progesterone (Primolut-Nor), which is different from what I had before.
Which has fewer side effects, Primolut-Nor or Provera? Will it cause the endometrium to thin out, resulting in no menstruation next time? I want my period to come naturally, and hearing the doctor say it could come naturally leaves me unsure whether to take medication or not.
It is currently the luteal phase; if I take medication, will it really help regulate my cycle, and will I have my period next month? Thank you, doctor...

Kunrao, 30~39 year old female. Ask Date: 2007/07/01

Dr. Li Guanghan reply Obstetrics and Gynecology


Hello: A.
There are many causes of irregular menstruation.
It is recommended that you come in for an examination, where we will perform an ultrasound and blood tests; if you have had sexual intercourse, we will also conduct a pelvic exam and Pap smear.
B.
Accumulation of menstrual blood in the uterine cavity is very rare in clinical practice and can be extremely painful.
C.
There are many products containing progesterone, and those with stronger luteal effects may have more significant side effects; Provera generally has relatively lower side effects, but its efficacy is not as strong as Primolut-Nor.
D.
Progesterone does not thin the endometrium; rather, it stabilizes the endometrium.
After discontinuation of the medication, the sudden drop in progesterone levels in the body can lead to the shedding of the endometrium, resulting in withdrawal bleeding that induces menstruation.
E.
If medication is not used, will menstruation occur? We need to first investigate the reasons for the absence of menstruation and whether the underlying cause has been resolved.
For example, if your amenorrhea is due to stress, then as long as the stress is not alleviated, your menstruation will likely remain irregular.
Hsinchu City Hospital, Department of Obstetrics and Gynecology.

Reply Date: 2007/07/01

More Info


Menstrual irregularities can be a complex issue, often stemming from a variety of underlying causes. It’s essential to understand the potential reasons for these irregularities, the treatment options available, and any concerns that may arise during the process.

Firstly, menstrual irregularities can be caused by hormonal imbalances, stress, weight changes, medical conditions such as polycystic ovary syndrome (PCOS), thyroid disorders, or even lifestyle factors. In your case, it seems that you have been experiencing irregular periods for six years and have been relying on medications like Provera (medroxyprogesterone) to induce menstruation. This indicates a potential hormonal imbalance, which is common in women with irregular cycles.

Regarding your specific questions:
1. Concerns about Retained Products: If you have not had a natural period since February and are concerned about something being retained in the uterus, it is crucial to consult your healthcare provider. They may recommend an ultrasound to check for retained products of conception or other abnormalities. If there is a concern about the uterine lining being too thick or if there are any polyps or fibroids, further evaluation may be necessary. It is generally advisable to follow your doctor's recommendations, but if you feel uncertain, seeking a second opinion can provide additional clarity.

2. Medication Comparison: Provera and Primolut-Nor (norethisterone) are both forms of progestin, but they may have different side effects for different individuals. Provera is often used to regulate periods and can sometimes lead to side effects such as mood changes, weight gain, or breast tenderness. Primolut-Nor may have a similar side effect profile, but some women find it to be better tolerated. It’s essential to discuss with your doctor which medication might be more suitable for you based on your medical history and current symptoms.

3. Effects on the Endometrium: Both medications can affect the endometrial lining. Progestins can help to thin the lining over time, which may lead to lighter periods or even amenorrhea (absence of menstruation) if used continuously. If your goal is to have regular menstrual cycles, it’s important to communicate this with your healthcare provider. They can help you find a balance between managing your symptoms and achieving a regular cycle.

4. Self-Induced Menstruation: The idea of allowing your body to regulate itself is appealing, but it may not be feasible if your body has not done so for an extended period. If you are currently in the luteal phase of your cycle and considering medication, it may help to induce a period. However, the effectiveness of this approach can vary, and it’s essential to have realistic expectations. Your doctor may suggest a specific regimen to help regulate your cycle while monitoring your response to the medication.

5. Urinary Symptoms and Inflammation: You mentioned experiencing a urinary tract infection (UTI) without typical symptoms like frequency or pain. It’s possible to have a UTI without classic symptoms, especially in women with hormonal imbalances. If your doctor has diagnosed you with a UTI, it’s important to follow their treatment plan. If symptoms persist or worsen, further investigation may be warranted to rule out other conditions.

In conclusion, managing menstrual irregularities often requires a multifaceted approach, including medication, lifestyle changes, and regular monitoring by a healthcare provider. It’s crucial to maintain open communication with your doctor about your symptoms, treatment preferences, and any concerns you may have. Regular follow-ups and possibly seeking a second opinion can also provide additional insights into your condition and help you achieve a more regular menstrual cycle.

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