Am I at Risk of Contracting Hepatitis B After Exposure? - Internal Medicine

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Will I be infected with hepatitis B?


Hello Doctor: Last week, I went to the hospital to check my hepatitis B antibodies, and the doctor said I have a level of 370.
These past few days, I think I may have come into contact with the blood of someone with hepatitis B.
I would like to ask if I could be infected with hepatitis B? Do I need to get tested again? Or should I receive a booster vaccine?

Xiao Ling, 20~29 year old female. Ask Date: 2007/10/23

Dr. Xiao Jingqin reply Internal Medicine


Hepatitis B antibodies provide protection against infection with the Hepatitis B virus.
You should be more concerned about Hepatitis C, HIV, and other bloodborne diseases, and it is advisable to get tested for those.
There is no need for a booster shot of the Hepatitis B vaccine, as you already have antibodies (the 370 indicates the titer of those antibodies as detected by that laboratory).

Reply Date: 2007/10/23

More Info


When it comes to the risk of contracting Hepatitis B after potential exposure, it's important to understand several key factors regarding the virus, vaccination, and the nature of the exposure itself.

Firstly, Hepatitis B is primarily transmitted through contact with infectious body fluids, particularly blood, semen, and vaginal secretions. The virus can be present in the blood of an infected person, and if that blood comes into contact with an open wound or mucous membranes, there is a risk of transmission. However, the likelihood of contracting the virus depends on several factors, including the viral load of the infected individual and the nature of the exposure.

In your case, you mentioned that you have a Hepatitis B antibody level of 370, which indicates that you have protective antibodies against the virus. This level suggests that you are immune to Hepatitis B, likely due to previous vaccination or recovery from an infection. Generally, individuals with adequate levels of Hepatitis B surface antibodies (anti-HBs) are considered protected against the virus and are at a very low risk of infection, even if they come into contact with the virus.

If you have had a recent exposure to blood from someone who is Hepatitis B positive, the risk of transmission is significantly reduced because of your existing immunity. However, if you are uncertain about your antibody levels or if there have been any changes in your health status, it may be prudent to consult with your healthcare provider. They might recommend a follow-up blood test to confirm your antibody levels and ensure that you remain protected.

Regarding vaccination, if you have confirmed that your antibody levels are adequate, there is typically no need to receive another dose of the vaccine. However, if your antibody levels were to drop below the protective threshold, a booster dose may be recommended. It’s essential to discuss this with your healthcare provider, who can provide personalized advice based on your medical history and current health status.

In summary, given your reported antibody levels, the risk of contracting Hepatitis B from the exposure you described is low. However, it is always wise to stay vigilant and consult with a healthcare professional if you have any concerns or if you experience any symptoms that could indicate an infection. Regular monitoring and maintaining your vaccination status are key components of preventing Hepatitis B infection.

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