Hyperthyroidism: Symptoms, Treatment, and Concerns - Internal Medicine

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Hyperthyroidism


Hello Dr.
Yang: I discovered symptoms of hyperthyroidism nearly six months ago.
I have reduced my medication from two pills a day to one and a half pills a day, and my thyroid hormone levels have returned to normal a month ago.
However, I have two questions for you: 1.
Can continuous medication lead to hypothyroidism? 2.
Is it possible for someone to be unable to gain weight due to hyperthyroidism and only start experiencing noticeable symptoms like palpitations after several years? (My parents have always said that my previous lower weight was due to hyperthyroidism, but I had no health issues before; I only noticed swelling in my neck and palpitations six months ago.
I have gained 4 kilograms in the past four months of medication and have already exceeded the standard weight.) Thank you!

Yenni, 20~29 year old female. Ask Date: 2007/11/15

Dr. Yang Hongzhi reply Internal Medicine


Hello: 1.
If the dosage is not reduced, it may lead to hypothyroidism.
2.
The likelihood of significant hyperthyroidism has been low for a long time.

Reply Date: 2007/11/15

More Info


Understanding hyperthyroidism is crucial for managing its symptoms and treatment effectively. Hyperthyroidism occurs when the thyroid gland produces excessive amounts of thyroid hormones, leading to a range of symptoms and potential complications. In your case, it seems you have been diagnosed with hyperthyroidism and have been undergoing treatment, which has resulted in a normalization of your thyroid hormone levels. However, you have raised two important questions that warrant further discussion.

1. Can continuous medication lead to hypothyroidism?
Yes, prolonged treatment for hyperthyroidism, particularly with antithyroid medications such as methimazole or propylthiouracil, can sometimes lead to hypothyroidism. This is because these medications work by inhibiting the production of thyroid hormones. If the dosage is too high or if the treatment continues for an extended period, it can suppress thyroid hormone production to the point where the thyroid becomes underactive, resulting in hypothyroidism. Regular monitoring of thyroid function tests (TFTs) is essential during treatment to ensure that hormone levels remain within the normal range. If you notice symptoms of hypothyroidism, such as fatigue, weight gain, cold intolerance, or depression, it is important to discuss these with your healthcare provider.

2. Can someone experience hyperthyroidism symptoms after years of being asymptomatic?
Yes, it is possible for individuals to have hyperthyroidism without noticeable symptoms for an extended period. Some people may have mild hyperthyroidism that does not present with significant symptoms until the condition progresses or is triggered by stress, illness, or other factors. In your case, it seems that you were asymptomatic for a long time, and the noticeable symptoms, such as a swollen neck and palpitations, only appeared recently. This can happen, especially in conditions like Graves' disease, where the autoimmune process can gradually lead to an increase in thyroid hormone levels. It’s also worth noting that weight changes can vary significantly among individuals with hyperthyroidism; some may lose weight, while others may not experience significant changes until the condition becomes more pronounced.

In summary, managing hyperthyroidism requires careful monitoring and communication with your healthcare provider. It is essential to have regular follow-ups to adjust medication dosages as needed and to monitor for any potential side effects, including the risk of developing hypothyroidism. Additionally, understanding the nature of your symptoms and their progression can help in managing your condition effectively. If you have concerns about your treatment or symptoms, do not hesitate to reach out to your healthcare provider for personalized advice and support.

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