Does Using Placenta-Based Night Cream Affect Male Fetus During Pregnancy? - Obstetrics and Gynecology

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There is no conclusive evidence to suggest that applying placental extract facial cream to the abdomen has any impact on a fetus, regardless of gender. However, it is always advisable for pregnant individuals to consult with their healthcare provider before using any topical products during pregnancy to ensure safety for both the mother and the developing fetus?


I am currently five months pregnant and have been using a facial night cream (applied all over my body) that contains the following ingredients: formulated with placenta and antioxidants vitamins A and E.
I am concerned about whether this will have any effects on my fetus.
Thank you!

ya, 20~29 year old female. Ask Date: 2007/11/21

Dr. Zhuang Zhijian reply Obstetrics and Gynecology


Hello, thank you for your inquiry.
I would like to respond to your question and provide some related advice as follows: Generally speaking, during pregnancy, it is recommended to avoid using medications unless absolutely necessary for treatment.
Even topical applications should be minimized whenever possible.
Lastly, I wish you safety and happiness!

Reply Date: 2007/11/21

More Info


Using placenta-based night cream during pregnancy raises valid concerns, especially regarding its potential effects on a developing fetus. In your case, you mentioned that you have been using a night cream containing placenta and antioxidants, specifically vitamins A and E, during your pregnancy.
Firstly, it is essential to understand that the placenta is an organ that develops in the uterus during pregnancy and plays a crucial role in nourishing the fetus. However, when it comes to topical products containing placenta, the implications are not straightforward. The placenta in cosmetic formulations is often derived from animal sources, and the safety of such products during pregnancy is not well-established.

The primary concern with using any topical product during pregnancy is the absorption of its ingredients into the bloodstream and their potential effects on the fetus. While the skin acts as a barrier, certain substances can penetrate and enter systemic circulation. In general, the use of topical creams is considered safer than oral medications, but caution is still advised.

Vitamin A, in particular, is a nutrient that requires careful monitoring during pregnancy. High doses of vitamin A, especially in the form of retinoids, have been associated with teratogenic effects, meaning they can cause developmental abnormalities in the fetus. However, the amount of vitamin A absorbed through topical application is typically much lower than that from oral supplements. The key is to ensure that the total intake of vitamin A from all sources remains within recommended limits during pregnancy.

Antioxidants like vitamin E are generally regarded as safe and beneficial during pregnancy. They play a role in protecting cells from oxidative stress and may support overall skin health. However, the specific effects of topical application of vitamin E in combination with other ingredients in your cream are not well-documented.

Given that you are currently five months pregnant and have been using this product regularly, it is advisable to consult with your healthcare provider or a dermatologist. They can provide personalized advice based on your medical history and the specific formulation of the cream you are using. They may recommend discontinuing the use of the cream if there are any concerns about its ingredients or if you experience any adverse reactions.

In summary, while the use of placenta-based night cream may not pose a significant risk, it is essential to approach the use of any topical products during pregnancy with caution. Always prioritize safety and consult with healthcare professionals to ensure the well-being of both you and your developing fetus. Additionally, consider exploring alternative skincare products that are specifically formulated for use during pregnancy, as these are often designed to minimize any potential risks.

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