The hepatitis B virus infection is currently very active among carriers?
A 31-year-old male, who is a carrier of hepatitis B, discovered during a health check that his liver enzyme levels were excessively high, ranging from 400 to nearly 500.
Further tests at a larger hospital revealed that he is actively infected with the virus, with a viral load of 640 million.
Although he does not fully understand the implications, the doctor has recommended a liver biopsy in three months, followed by treatment.
Initially, he did not perceive the severity of his condition, but after reviewing a booklet provided by the doctor, he realized that his illness is quite serious.
The treatment is out-of-pocket, and he found online that it could cost around 200,000 NTD for six months.
However, he also came across information suggesting that some hospitals may offer coverage under the national health insurance.
He is now uncertain about what steps to take next.
Jenny, 30~39 year old female. Ask Date: 2007/11/21
Dr. Chen Jianhong reply Gastroenterology and Hepatology
Hello Jenny!
1.
According to the doctor, 640 million → without the unit of measurement attached, if the unit is copies/mL, then the viral load is very high.
2.
A biopsy is recommended before treatment → Is interferon therapy suggested? If so, your physician may want to apply for National Health Insurance coverage, as this is a requirement from the National Health Insurance Administration.
A liver biopsy is necessary for coverage; if you prefer not to undergo a liver biopsy, the cost would be approximately 200,000 TWD.
However, the information in the letter is quite vague.
Could you please clarify whether your e-antigen is negative or positive?
3.
You will need to wait another three months, as at least six months of data is required (according to National Health Insurance regulations).
Additionally, this will allow for monitoring of subsequent developments.
4.
Are there any well-known medical institutions related to the treatment of viral infections? → No, the hepatobiliary department of a hospital will suffice.
5.
The information you provided is insufficient; if possible, please provide more details.
6.
How long has your family member been a carrier? Is their e-antigen negative or positive? Do they have e-antibodies? What is their liver enzyme level (ALT)? What was it previously? Is there an ultrasound report? What are the bilirubin levels, albumin levels, and coagulation time test results? Is there a co-infection with hepatitis C? How old are they?
Reply Date: 2007/11/21
More Info
Active hepatitis B infection is a significant health concern that requires careful management and understanding. As a 31-year-old patient who has transitioned from being a carrier to an active infection, it’s essential to grasp the implications of your condition and the treatment options available.
Understanding Active Hepatitis B Infection
Hepatitis B is a viral infection that attacks the liver and can cause both acute and chronic diseases. When the virus is active, it means that it is replicating in your body, which can lead to liver inflammation, damage, and potentially serious complications such as cirrhosis or liver cancer. Your recent lab results indicating elevated liver enzymes (AST and ALT) and a high viral load (640 million copies/mL) suggest that your liver is under significant stress, and immediate action is necessary.
Treatment Options
The treatment for active hepatitis B typically involves antiviral medications. The most commonly prescribed antiviral drugs include tenofovir and entecavir, which are effective in suppressing the virus and reducing liver inflammation. It’s crucial to follow your physician's advice regarding treatment, as they will tailor the approach based on your specific situation, including liver function tests and the extent of liver damage.
Financial Considerations
You mentioned concerns about the cost of treatment, which can indeed be a burden. In Taiwan, some antiviral treatments for hepatitis B may be covered by the National Health Insurance (NHI), depending on specific criteria such as the severity of the disease and the type of medication prescribed. It’s advisable to discuss this with your healthcare provider or the hospital’s billing department to clarify what costs may be covered and what your out-of-pocket expenses might be.
Importance of Monitoring
Your doctor has recommended a liver biopsy in three months, which is a critical step in assessing the extent of liver damage (fibrosis or cirrhosis). This procedure will provide valuable information about the health of your liver and help guide further treatment decisions. Regular monitoring of liver function tests and viral load is essential to evaluate the effectiveness of the treatment and make necessary adjustments.
Lifestyle Modifications
In addition to medical treatment, lifestyle changes can significantly impact your liver health. Here are some recommendations:
1. Avoid Alcohol: Alcohol can exacerbate liver damage, so it’s crucial to abstain completely.
2. Healthy Diet: Focus on a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Avoid fatty, fried, and processed foods.
3. Regular Exercise: Engage in regular physical activity to maintain a healthy weight and improve overall health.
4. Stress Management: High stress can negatively affect your immune system. Consider practices such as yoga, meditation, or other relaxation techniques.
Emotional Support
Receiving a diagnosis of active hepatitis B can be overwhelming. It’s essential to seek support from healthcare professionals, family, and friends. Joining support groups for individuals with hepatitis B can also provide valuable emotional support and practical advice from others who understand what you’re going through.
Conclusion
Active hepatitis B infection is a serious condition that requires prompt and effective management. By adhering to your treatment plan, making necessary lifestyle changes, and staying informed about your condition, you can take significant steps toward maintaining your liver health. Don’t hesitate to reach out to your healthcare provider with any questions or concerns you may have regarding your treatment and overall health. Remember, you are not alone in this journey, and there are resources available to help you navigate your diagnosis.
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