Your Blood Test Results: What Do Eosinophils, PDW, and P-LCR Mean? - Family Medicine

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Consulting a physician: Recently, my blood test results showed three abnormal findings: 1.
Eosinophils (EOSINOPHILS) percentage is 3.7 (normal range: 1-3) 2.
Platelet Distribution Width (PDW) FL is 9.9 (normal range: 10-16) 3.
Platelet-Large Cell Ratio (P-LCR) percentage is 17.9 (normal range: 20-45).
What do these values indicate? Thank you! PAT

PAT, 50~59 year old female. Ask Date: 2008/05/13

Dr. Lai Junlong reply Family Medicine


Hello, in response to your questions:
1.
Before examining the white blood cell differential, one should first look at the total white blood cell count (which typically ranges from 4,000/µL to 11,000/µL).
An abnormal white blood cell differential only has clinical significance if the total count is abnormal.
2.
Eosinophils (EOSINOPHILS) may increase in cases of allergies or parasitic infections, and they can significantly rise in individuals with specific sensitivities.
3.
Platelet Distribution Width (PDW) measures the variability in platelet size.
A wider distribution may indicate overproduction, which could suggest underlying destruction or rapid consumption of platelets (potentially due to bleeding or splenomegaly).
4.
The Platelet-Large Cell Ratio (P-LCR) has limited clinical significance.
Dr.
Chuen-Lung Lai

Reply Date: 2008/05/13

More Info


Understanding blood test results can be quite complex, but it is essential for interpreting your health status. In your case, you have three specific parameters that are outside the normal range: Eosinophils (EOS), Platelet Distribution Width (PDW), and Platelet-Large Cell Ratio (P-LCR). Let's break down each of these components.

1. Eosinophils (EOS): Your eosinophil percentage is 3.7%, which is above the normal range of 1-3%. Eosinophils are a type of white blood cell that play a crucial role in the body's immune response, particularly in combating parasitic infections and mediating allergic reactions. An elevated eosinophil count can indicate several conditions, including allergies, asthma, autoimmune diseases, and parasitic infections. It may also be associated with certain malignancies or drug reactions. Therefore, it is essential to consider any symptoms you may be experiencing, such as allergic reactions, respiratory issues, or gastrointestinal symptoms, which could provide further context for this elevation.

2. Platelet Distribution Width (PDW): Your PDW is 9.9 FL, which is slightly below the normal range of 10-16 FL. PDW measures the variation in platelet size in the blood. A low PDW can indicate a uniformity in platelet size, which may be associated with conditions such as thrombocytopenia (low platelet count) or other hematological disorders. It is important to correlate this finding with your platelet count and any clinical symptoms you may have, as a low PDW alone may not indicate a specific disease but could suggest a need for further investigation.

3. Platelet-Large Cell Ratio (P-LCR): Your P-LCR is 17.9%, which is below the normal range of 20-45%. P-LCR measures the proportion of large platelets in the blood. A low P-LCR can suggest that there are fewer larger platelets, which may be associated with conditions affecting platelet production or function. Similar to PDW, this parameter should be interpreted in conjunction with your overall platelet count and any clinical symptoms.

In summary, the abnormalities in your blood test results suggest that there may be underlying issues that warrant further investigation. Elevated eosinophils could indicate an allergic response or other immune-related conditions, while the low PDW and P-LCR may point to issues with platelet production or function. It is crucial to discuss these results with your healthcare provider, who can evaluate them in the context of your overall health, symptoms, and any other relevant tests. They may recommend additional tests or referrals to specialists, such as an allergist or hematologist, to further assess your condition.

In conclusion, while individual blood test results can provide valuable insights, they must be interpreted in the context of your overall health and clinical picture. Always consult with your healthcare provider for a comprehensive evaluation and personalized medical advice.

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