Avascular Necrosis: Causes, Symptoms, and Treatment Options - Orthopedics

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Osteonecrosis


Hello Dr.
Hong,
I had a serious illness a year and a half ago.
It started with a cold that led to aspiration pneumonia, for which I was treated with antibiotics.
About a month later, I developed meningitis (an X-ray also revealed inflammation in the brainstem) and was admitted to the intensive care unit, where I received a large amount of corticosteroids for about a month.
I experienced complete paralysis but through intensive rehabilitation, I have made a good recovery.
However, my current concern is that due to the extensive use of corticosteroids, an MRI revealed localized necrosis in my right hip joint and both arm joints, with the right arm joint being more severely affected.
I have been taking Fosamax for nearly a year, and while there has been significant improvement in my right hip joint, both arm joints are still very painful.
Additionally, the joint at the base of my right hand is swollen and painful, and I have not yet seen a doctor about this.

I would like to ask Dr.
Hong why, despite taking Fosamax for some time, my hip joint has improved significantly while there has been no noticeable improvement in my arm joints.
Besides painkillers, are there any other medications that could help my current condition? (P.S.
My bone density is good.) Also, why is my right hand experiencing these issues? Thank you for your response, Dr.
Hong.

Pipi, 20~29 year old female. Ask Date: 2008/06/30

Dr. Hong Ximing reply Orthopedics


Based on the current situation, it is essential to first determine the extent of avascular necrosis, including the right hip and shoulder joints.
This cannot be resolved solely with medication; a prompt examination at the hospital is necessary, including MRI and nuclear medicine evaluations.

Reply Date: 2008/06/30

More Info


Avascular necrosis (AVN), also known as osteonecrosis, is a condition that occurs when there is a loss of blood supply to a bone, leading to the death of bone tissue. This can result in joint pain, limited range of motion, and eventually, joint collapse if not treated properly. Understanding the causes, symptoms, and treatment options for AVN is crucial, especially for individuals like yourself who have experienced significant health challenges and are now facing the repercussions of steroid use.

Causes of Avascular Necrosis:
AVN can be caused by a variety of factors, but one of the most common is the prolonged use of corticosteroids, which you mentioned in your case. Corticosteroids can interfere with the body’s ability to maintain healthy blood flow to the bones. Other causes include excessive alcohol consumption, certain medical conditions (such as sickle cell disease or lupus), and trauma or injury to the bone. In your situation, the use of high doses of steroids following your severe illness likely contributed to the development of AVN in your hip and shoulder joints.

Symptoms of Avascular Necrosis:
The symptoms of AVN can vary depending on the stage of the disease. Early on, you may experience mild pain or discomfort in the affected joint, which can be mistaken for other conditions. As the disease progresses, the pain may become more severe and persistent, especially during weight-bearing activities. You may also notice swelling and reduced range of motion in the affected joints. In your case, the pain in your shoulders and the swelling in your right hand could be indicative of AVN affecting those areas.

Treatment Options:
The treatment for AVN depends on several factors, including the stage of the disease, the location of the necrosis, and the overall health of the patient. Here are some common treatment options:
1. Medications: Pain relief is often the first step in managing AVN. Nonsteroidal anti-inflammatory drugs (NSAIDs) can help reduce pain and inflammation. In your case, you mentioned using pain medications, but it may be worth discussing with your doctor the possibility of adjusting your pain management plan or exploring other medications that could be more effective.

2. Physical Therapy: Engaging in physical therapy can help improve joint function and reduce pain. A physical therapist can provide exercises tailored to your specific needs and limitations.

3. Surgical Options: If conservative treatments do not provide relief, surgical options may be considered. These can include core decompression (removing a portion of the bone to reduce pressure and increase blood flow), bone grafting, or joint replacement surgery in more advanced cases.

4. Lifestyle Modifications: Reducing weight-bearing activities on the affected joints can help alleviate pain and prevent further damage. Additionally, avoiding alcohol and maintaining a healthy diet can support overall bone health.

5. Alternative Therapies: Some patients find relief through alternative therapies such as acupuncture or chiropractic care, though these should be discussed with your healthcare provider to ensure they are safe and appropriate for your condition.

Regarding your specific question about why your hip joint has improved while your shoulder joints remain painful, this can be attributed to several factors, including the extent of necrosis, the specific joint's anatomy, and how well each joint responds to treatment. Each joint may heal at different rates, and the degree of damage can vary significantly.

Lastly, the swelling and pain in your right hand may be due to several factors, including inflammation, overuse, or even referred pain from the shoulder. It is essential to consult with your healthcare provider to evaluate these symptoms further and adjust your treatment plan accordingly.

In conclusion, managing avascular necrosis requires a comprehensive approach that includes pain management, physical therapy, and possibly surgical intervention. Regular follow-ups with your healthcare provider are crucial to monitor your condition and make necessary adjustments to your treatment plan. Your proactive approach to understanding your condition and seeking answers is commendable, and I encourage you to continue advocating for your health.

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