One-third of the heart is necrotic?
Hello doctor, I would like to ask if Troponin is a test for myocardial infarction? If so, is a value of 0.75 considered high? And is a value of 14.7 considered dangerous? If these values are detected, how should the physician proceed?
Xin Yi Si, 30~39 year old female. Ask Date: 2008/07/07
Dr. Lin Jixiong reply Cardiology
Hello: Troponin is a marker used to assess myocardial infarction.
If there are changes in the detected levels, particularly an increase, a cardiologist should assist in interpreting the diagnosis.
However, there are various clinical conditions that can also lead to elevated troponin levels, not just myocardial infarction.
Therefore, physicians must make decisions based on the patient's clinical condition.
This issue is not suitable for explanation to the general public with limited clinical experience, as it may lead to misinterpretation and misunderstanding.
Sincerely, Dr.
Lin Chi-Hsiung, Taoyuan General Hospital.
Reply Date: 2008/07/07
More Info
Troponin is indeed a critical biomarker used in the diagnosis of myocardial infarction (heart attack) and other forms of cardiac injury. Troponin proteins (specifically troponin I and troponin T) are found in cardiac muscle and are released into the bloodstream when there is damage to the heart muscle. Therefore, elevated levels of troponin can indicate myocardial injury, making it a vital tool in emergency medicine and cardiology.
In your case, a troponin level of 0.75 ng/mL is considered elevated, as the normal range for troponin I is typically below 0.04 ng/mL, although this can vary slightly depending on the laboratory and the specific assay used. A troponin level of 14.7 ng/mL is significantly high and is indicative of a substantial myocardial injury, which could be due to a heart attack or other serious cardiac conditions.
When troponin levels are elevated, especially at such high levels, it prompts immediate clinical evaluation. The physician would typically follow a structured approach:
1. Clinical Assessment: The physician will assess the patient's symptoms, medical history, and risk factors for coronary artery disease (CAD). Symptoms such as chest pain, shortness of breath, or other signs of cardiac distress will be taken into account.
2. ECG Monitoring: An electrocardiogram (ECG) will be performed to look for signs of ischemia or infarction. Changes in the ECG, such as ST-segment elevation or depression, can provide additional information about the severity and type of cardiac event.
3. Further Testing: Depending on the initial findings, additional tests may be ordered, including imaging studies (like echocardiography or coronary angiography) to assess heart function and blood flow through the coronary arteries.
4. Treatment: If a heart attack is confirmed or highly suspected, treatment will be initiated promptly. This may include medications such as antiplatelet agents (e.g., aspirin, clopidogrel), anticoagulants, beta-blockers, ACE inhibitors, and statins. In some cases, urgent interventions such as percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) may be necessary to restore blood flow to the heart muscle.
5. Monitoring and Follow-Up: Patients with elevated troponin levels will be closely monitored in a hospital setting, often in a cardiac care unit, to manage any complications and to ensure appropriate recovery.
In summary, troponin levels are a crucial part of diagnosing and managing myocardial infarction. A level of 0.75 ng/mL is elevated and warrants further investigation, while a level of 14.7 ng/mL is alarming and indicates a significant risk of serious cardiac events. Immediate medical attention is essential in such cases to ensure timely and effective treatment. If you or someone you know is experiencing symptoms of a heart attack, it is vital to seek emergency medical care immediately.
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