Effective Treatments for Acid Reflux After Esophageal Surgery - Gastroenterology and Hepatology

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Gastroesophageal reflux disease (GERD)


Hello Dr.
Chang, I had surgery for esophageal cancer nine years ago, during which my esophagus and part of my stomach were removed.
Now my stomach is located in the thoracic cavity, but I have been experiencing gastroesophageal reflux symptoms.
I often wake up choking at night.
Currently, I am taking Pozola 40mg, one tablet in the morning and one in the evening, and Mucaine 5mg before each meal, but the results are poor.
During the day it's manageable, but at night I have to sleep sitting up.
Are there any other more effective medications available, either covered by insurance or out-of-pocket? I am currently under continuous follow-up at the thoracic surgery department; should I also consider seeing a gastroenterologist?

Er Guo Tou, 40~49 year old female. Ask Date: 2008/07/25

Dr. Zhang Siyuan reply Gastroenterology and Hepatology


To Chikuang: Your condition appears to be more pronounced than typical gastroesophageal reflux, with nighttime gastric acid reflux reaching the throat, leading to coughing.
Pantoprazole has been used at a dosage of 80 mg per day, which is double the standard treatment for gastroesophageal reflux disease, yet it remains ineffective.
In addition to the possibility that the drug's efficacy may be interfered with by Mucaine, there is likely a relaxation between the residual stomach and esophagus.
You should return to the thoracic surgery department for reassessment to determine if a repair surgery is necessary.
Please do not increase the medication dosage further.
Lesein Rehabilitation Hospital, Gastroenterology and Hepatology Department, Dr.
Zhang Siyuan.

Reply Date: 2008/07/25

More Info


After undergoing esophageal surgery, particularly for conditions like esophageal cancer, many patients experience persistent acid reflux, which can significantly affect their quality of life. Your situation, where you have been experiencing acid reflux symptoms despite being on medications like Pozola (a proton pump inhibitor) and Mucaine (an antacid), is not uncommon. Let's explore effective treatments and management strategies for acid reflux post-surgery.


Understanding Acid Reflux After Esophageal Surgery
Acid reflux, or gastroesophageal reflux disease (GERD), occurs when stomach acid flows back into the esophagus, causing symptoms such as heartburn, regurgitation, and discomfort. After esophageal surgery, the anatomy of the gastrointestinal tract changes, which can lead to increased reflux symptoms. Factors contributing to this include:
1. Altered Anatomy: The surgical removal of the esophagus and part of the stomach can affect the normal functioning of the lower esophageal sphincter (LES), which is responsible for preventing acid reflux.

2. Reduced Gastric Capacity: With a smaller stomach, the ability to hold food and acid is diminished, potentially leading to increased pressure and reflux.

3. Delayed Gastric Emptying: Surgery can sometimes slow down the emptying of the stomach, leading to increased pressure and reflux.


Current Treatment Options
1. Proton Pump Inhibitors (PPIs): Medications like Pozola (esomeprazole) are commonly prescribed to reduce stomach acid production. If you find that your current dosage is ineffective, consult your physician about adjusting the dosage or switching to a different PPI, such as omeprazole or lansoprazole. Sometimes, a higher dose or a different formulation may provide better relief.

2. Antacids and H2 Blockers: While Mucaine is an antacid that can provide quick relief, consider discussing the addition of H2 blockers like ranitidine or famotidine with your doctor. These medications can help reduce acid production and may be used in conjunction with PPIs.

3. Lifestyle Modifications: Implementing lifestyle changes can significantly impact reflux symptoms:
- Dietary Changes: Avoid trigger foods such as spicy foods, citrus, chocolate, caffeine, and fatty foods. Eating smaller, more frequent meals can also help.

- Posture: Avoid lying down immediately after eating. Elevating the head of your bed can help reduce nighttime symptoms.

- Weight Management: If applicable, maintaining a healthy weight can decrease abdominal pressure and reduce reflux.

4. Surgical Options: If medications and lifestyle changes do not provide adequate relief, surgical options may be considered. Procedures like fundoplication can help reinforce the LES and prevent reflux. However, given your history of esophageal surgery, this would require careful evaluation by a gastroenterologist and possibly a surgeon specializing in reflux surgery.

5. Gastroenterology Consultation: Since you are currently under the care of a thoracic surgeon, it may be beneficial to also consult a gastroenterologist. They can perform further evaluations, such as esophageal manometry or pH monitoring, to assess the severity of your reflux and tailor a treatment plan specifically for your needs.


Conclusion
Managing acid reflux after esophageal surgery can be challenging, but with a comprehensive approach that includes medication adjustments, lifestyle changes, and possibly further surgical evaluation, you can find relief from your symptoms. It is essential to maintain open communication with your healthcare providers and advocate for your health needs. If your current treatment is not effective, do not hesitate to seek a second opinion or additional consultations to explore all available options.

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