PDRAB Infections in Long-Term Hospitalized Patients - Surgery

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PDRAB (Pseudomon


Some long-term hospitalized patients may develop infections with PDRAB (Pseudomonas aeruginosa with multidrug resistance) during their hospital stay.
During the infection period, patients may experience various complications, including prolonged fever, increased respiratory distress, delayed wound healing, and potential sepsis.
If a patient is discharged home, there is a risk of transmitting PDRAB to family members, especially if proper hygiene and infection control measures are not followed.
However, PDRAB is primarily an opportunistic pathogen, and healthy individuals are generally at lower risk of infection.

xia t, 20~29 year old female. Ask Date: 2008/07/26

Dr. Huang Yuanhui reply Surgery


1.
PDRAB is increasingly prevalent in hospitals across Taiwan, associated with the complexity of patients' conditions, advancing age, and the use of antibiotics.
Once a patient carries PDRAB, they may become an asymptomatic carrier or may develop an actual infection.
Infections caused by PDRAB are currently very difficult to treat and have a high mortality rate.
If a patient improves and is discharged, it is important to determine whether they are still a carrier.
If the patient still harbors this bacterium, it is recommended that family members wash their hands after caring for or visiting them.
This bacterium does not adversely affect healthy individuals; they just need to be mindful of hand hygiene.

Reply Date: 2008/07/26

More Info


PDRAB, or Pandrug-Resistant Acinetobacter baumannii, is a significant concern in healthcare settings, particularly among long-term hospitalized patients. This bacterium is notorious for its resistance to multiple antibiotics, making infections difficult to treat and often leading to severe complications. Understanding the implications of PDRAB infections in hospitalized patients is crucial for both medical professionals and families of patients.


Problems Associated with PDRAB Infections
Patients who acquire PDRAB infections during their hospital stay may experience a range of complications. These can include:
1. Severe Infections: PDRAB can lead to various types of infections, including pneumonia, bloodstream infections, and wound infections. These infections can be particularly severe in patients with weakened immune systems or underlying health conditions.

2. Prolonged Hospitalization: The presence of a PDRAB infection often necessitates extended hospital stays due to the complexity of treatment and the need for isolation to prevent the spread of the bacteria.

3. Increased Mortality Risk: Studies have shown that infections caused by PDRAB are associated with higher mortality rates, particularly in critically ill patients or those with comorbidities.

4. Complications from Treatment: The treatment of PDRAB infections may involve the use of last-resort antibiotics, which can have significant side effects and may not always be effective. Additionally, the need for invasive procedures, such as intubation or central line placement, can increase the risk of further infections.

5. Psychological Impact: The stress of dealing with a resistant infection can take a toll on both patients and their families, leading to anxiety and uncertainty about the patient's prognosis.


Risk of Transmission to Family Members
When a patient infected with PDRAB is discharged from the hospital, the risk of transmitting the infection to family members is generally low, but it is not negligible. Here are some key points to consider:
1. Asymptomatic Carriers: Some patients may become asymptomatic carriers of PDRAB, meaning they can harbor the bacteria without showing any signs of infection. In such cases, they may not pose a significant risk to others, but precautions should still be taken.

2. Infection Control Practices: If the patient is still a carrier of PDRAB upon discharge, it is essential for family members to practice good hygiene, particularly handwashing. This is the most effective way to prevent the spread of bacteria. Family members should wash their hands thoroughly after caring for the patient or coming into contact with their belongings.

3. Environmental Contamination: PDRAB can survive on surfaces for extended periods. Therefore, cleaning and disinfecting frequently touched surfaces in the home can help reduce the risk of transmission.

4. Health Status of Family Members: Healthy individuals are generally at low risk of contracting PDRAB infections from carriers. However, those with compromised immune systems or underlying health conditions should take extra precautions.

5. Follow-Up Care: It is advisable for discharged patients to have follow-up appointments with their healthcare providers to monitor their health status and ensure that any remaining bacteria are being managed appropriately.


Conclusion
PDRAB infections pose significant challenges for long-term hospitalized patients, leading to severe health complications and increased mortality risk. While the risk of transmitting PDRAB to family members upon discharge is relatively low, it is essential to maintain strict hygiene practices to mitigate any potential risks. Families should be educated about the nature of PDRAB, the importance of hand hygiene, and the need for follow-up care to ensure the well-being of both the patient and their loved ones. By understanding these factors, families can better navigate the complexities of PDRAB infections and contribute to a safer home environment.

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