Oligohydramnios: Risks, Treatments, and Decisions - Rare Disease

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I have been diagnosed with oligohydramnios?


Last week during my routine prenatal check-up, the doctor informed me that I have low amniotic fluid and discussed its severity.
I was referred to China Medical University Hospital for a high-level ultrasound examination.
Yesterday, the results of the high-level ultrasound showed that the baby's kidneys appear to be normal, growth in all areas is also normal, and the placental function seems to be normal.
However, the amniotic fluid is still too low, with an amniotic fluid index of only 2.5.
I am currently 21 weeks pregnant, and the doctor mentioned that if I go beyond 24 weeks, regulations prohibit elective induction.
Therefore, I need to make a decision quickly.
I really do not want to give up on my baby, but I am also very concerned about potential growth issues for the baby.
It is indeed a difficult decision.
Amnioinfusion seems to be a good option, but I wonder if the current technology for amnioinfusion is mature.
Are there any risks or complications associated with it? What is the success rate?

Hui, 20~29 year old female. Ask Date: 2008/08/13

Dr. Chen Ming reply Rare Disease


Hello, I apologize for not addressing your question earlier as I was out of the country for a conference.
Regarding your situation, if there is no rupture of membranes and no infection, amniocentesis is usually the most advisable procedure.
I have indeed performed many amniocenteses, and in recent years, other hospitals have also started to perform them, which is not particularly dangerous.
However, I recommend first conducting a fetal chromosome analysis.
Typically, this is done by amniocentesis, but if there is a low amount of amniotic fluid, chorionic villus sampling (CVS) can be performed to confirm that it is not caused by chromosomal abnormalities.
If you later decide to forgo the pregnancy, that is understandable, but it is important to conduct some antibody tests after the postpartum period to ensure that the mother does not have an underlying immune disorder.
I have encountered several similar situations in the past.
Sincerely, Ming-Ching Chen, Director of the Department of Genetic Medicine, Chang Gung Memorial Hospital, 9.2.2008.

Reply Date: 2008/08/13

More Info


Oligohydramnios, or low amniotic fluid, is a condition that can pose significant risks during pregnancy. It is defined as an amniotic fluid index (AFI) of less than 5 cm or a single deepest pocket of fluid measuring less than 2 cm. In your case, with an AFI of 2.5 at 21 weeks of gestation, it is understandable that you are feeling anxious about the implications for your baby's health and your options moving forward.


Risks Associated with Oligohydramnios
1. Fetal Development: Amniotic fluid plays a crucial role in fetal development. It cushions the baby, allows for movement, and is essential for lung development. Low levels of amniotic fluid can lead to complications such as pulmonary hypoplasia (underdeveloped lungs), limb deformities, and facial deformities due to compression (part of a condition known as Potter's sequence).

2. Placental Function: Although your placenta appears to be functioning normally, oligohydramnios can sometimes indicate placental insufficiency, which can affect nutrient and oxygen delivery to the fetus.

3. Increased Risk of Complications: Oligohydramnios can increase the risk of complications during labor, including umbilical cord compression, which can lead to fetal distress.


Treatment Options
1. Monitoring: Close monitoring is essential. Regular ultrasounds can help assess the baby's growth and well-being, as well as the amount of amniotic fluid.

2. Hydration: Increasing maternal hydration may help improve amniotic fluid levels. Drinking plenty of fluids can sometimes lead to a slight increase in fluid levels.

3. Amnioinfusion: This procedure involves the infusion of sterile fluid into the amniotic cavity through a catheter inserted into the uterus. It can temporarily increase the volume of amniotic fluid and relieve umbilical cord compression during labor. However, it is generally more effective in cases of oligohydramnios diagnosed closer to term.

4. Delivery Decisions: If oligohydramnios is severe and poses risks to the fetus, early delivery may be considered. However, as you mentioned, regulations may limit the ability to induce labor before a certain gestational age (in your case, 24 weeks).

Amnioinfusion: Risks and Success Rates
Amnioinfusion is a relatively safe procedure, but like any medical intervention, it carries some risks, including:
- Infection: Introducing fluid into the uterus can increase the risk of infection.

- Uterine Overdistension: Too much fluid can cause the uterus to stretch excessively, which may lead to complications.

- Preterm Labor: There is a slight risk that the procedure could trigger contractions.

The success rate of amnioinfusion in alleviating complications associated with oligohydramnios is generally favorable, particularly in cases where cord compression is a concern. However, it is not a guaranteed solution and may not resolve the underlying issue of low amniotic fluid.


Making Decisions
Given your situation, it is crucial to have open discussions with your healthcare provider about the risks and benefits of each option. Considerations should include:
- The current health of your baby and any potential complications.

- Your emotional and psychological readiness for the possible outcomes.

- The potential benefits of interventions like amnioinfusion versus the risks involved.

It is completely understandable to feel torn between wanting to protect your baby and the fear of potential complications. Seeking support from healthcare professionals, counselors, or support groups can also help you navigate this challenging time. Remember, you are not alone in this, and there are resources available to help you make the best decision for you and your baby.

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