Recent Decreased Libido in Men: Possible Causes and Solutions - Urology

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I have been experiencing a lack of libido in recent months?


Hello, doctor! I am a 36-year-old male and have been experiencing a lack of libido in recent months (although I believe my erectile function is normal, as I sometimes wake up with an erection).
What could be the reason for this? Is it a sign of deterioration? I have had my testosterone levels tested, and they are normal.
Regarding medications, I am taking antidepressants: TOFRANIL (Imipramine) 7 tablets a day, XANAX (Alprazolam) 2 tablets a day, TEGOL (Trazodone) 2 tablets a day, and DEANXIT (Flupentixol and Melitracen) 3 tablets a day, as well as a hair growth supplement: Rogaine (Minoxidil) 1 tablet a day.
If the medications are affecting my libido, I should note that I was on these same medications four years ago and did not experience a lack of libido at that time.

JJ, 30~39 year old female. Ask Date: 2008/08/23

Dr. Lin Hexing reply Urology


Hello Sir: Thank you for your inquiry.
I would like to address your question and provide the following recommendations: Based on your description, you do not have erectile dysfunction, but you are experiencing a lack of libido.
The medication Finasteride (commonly known as Propecia) you are taking may be contributing to this issue, as it can significantly suppress testosterone levels.
Although you have been taking this medication for four years, prolonged use can still have an impact.
I recommend that you discontinue Finasteride and consider alternative treatments for hair loss, such as topical minoxidil.
It would also be advisable to discuss the Finasteride medication with your physician.
Lastly, I wish you peace and happiness.

Reply Date: 2008/08/23

More Info


Decreased libido in men can be a multifaceted issue, often influenced by a combination of psychological, physiological, and lifestyle factors. At 36 years old, experiencing a decline in sexual desire can be concerning, especially when other aspects of sexual function, such as erectile capability, remain intact.
Firstly, it's important to consider the role of medications. You mentioned taking several psychiatric medications, including TOFRANIL (a tricyclic antidepressant), XANAX (a benzodiazepine), TEGOL (an antidepressant), and DEANXIT (an antidepressant). Antidepressants, particularly those that affect serotonin levels, are known to have sexual side effects, including decreased libido. While you noted that you did not experience this issue four years ago while on similar medications, individual responses to medications can change over time. Factors such as changes in dosage, the introduction of new medications, or even changes in your mental health status can all contribute to variations in side effects.

In addition to medication, psychological factors can significantly impact libido. Stress, anxiety, and depression can all lead to a decrease in sexual desire. The fact that you are taking multiple medications for anxiety and depression suggests that these issues may be at play. It’s also worth considering any recent life changes or stressors that may have contributed to your current feelings.

Another aspect to explore is hormonal balance. You mentioned that your testosterone levels are normal, which is a positive sign, as low testosterone can lead to decreased libido. However, other hormonal imbalances, such as thyroid dysfunction or elevated prolactin levels, can also affect sexual desire. It might be beneficial to discuss with your healthcare provider the possibility of further hormonal evaluations if you have not already done so.

Lifestyle factors should not be overlooked either. Diet, exercise, sleep quality, and substance use (including alcohol and recreational drugs) can all influence libido. Regular physical activity and a balanced diet can enhance overall well-being and potentially improve sexual desire. Additionally, ensuring adequate sleep is crucial, as fatigue can significantly impact libido.

If you suspect that your medications are contributing to your decreased libido, it is essential to have an open discussion with your prescribing physician. They may consider adjusting your medication regimen or exploring alternative treatments that have a lower risk of sexual side effects. It’s crucial not to stop or alter your medications without professional guidance, as this can lead to withdrawal symptoms or a resurgence of underlying mental health issues.

In conclusion, decreased libido can arise from a complex interplay of factors, including medication side effects, psychological influences, hormonal balance, and lifestyle choices. It is advisable to consult with a healthcare professional who can provide a comprehensive evaluation and tailor a treatment plan that addresses your specific situation. This may include medication adjustments, therapy for underlying psychological issues, or lifestyle modifications aimed at improving overall health and well-being.

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