Lip Blisters in Infants: Causes and Concerns - Pediatrics

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Blisters on the lips?


My baby was born on September 13, and yesterday I noticed that his lips were white.
Upon closer inspection, it seems like there are clusters of blisters.
After observing for a day, I found that they become less noticeable when he doesn't drink milk, but they reappear after he drinks milk.
Is this normal?

Zhicheng, 20~29 year old female. Ask Date: 2008/09/25

Dr. Xiao Kaiwen reply Pediatrics


The white appearance of an infant's lips may simply be a normal distribution of pigmentation, or it could be oral thrush (a fungal infection, though it is less common in newborns just a few days old).
If the white spots appear after feeding and form blisters, they are more likely to be normal "suction blisters." When breastfeeding, the lips, which are originally elongated, form a circular shape to envelop the nipple, causing the mucosal surfaces of the lips to compress against each other, resembling a row of pastries.
However, it is also important to consider other possibilities, such as viral infections, and it is advisable to consult a pediatrician.

Reply Date: 2008/09/25

More Info


Lip blisters in infants can be concerning for parents, especially when they appear suddenly and seem to be associated with feeding. In your case, it sounds like your baby has developed white blisters on the lips that become more pronounced after drinking milk. This situation could be attributed to several factors, and understanding the underlying causes is essential for addressing your concerns.

One common cause of lip blisters in infants is a condition known as "milk blister" or "nipple blister." This occurs when the skin on the lips or around the mouth becomes irritated due to friction or suction during breastfeeding or bottle-feeding. The blisters may appear white or clear and can be more noticeable after feeding when the area is moist. This type of blister is generally harmless and tends to resolve on its own as the skin heals.

Another possibility is that the blisters are related to a reaction to the milk itself. Some infants may develop a sensitivity or mild allergic reaction to cow's milk protein, especially if they are consuming formula that contains cow's milk. This can lead to localized skin reactions, including blisters or rashes around the mouth. If you suspect that the blisters are related to the type of milk your baby is consuming, it may be worth discussing with your pediatrician the possibility of trying a hypoallergenic formula or a different feeding approach.

Additionally, oral thrush, a fungal infection caused by Candida, can also present as white patches or blisters in the mouth and on the lips. This condition is more common in infants and can occur if the baby has been exposed to antibiotics or if the mother has a yeast infection. If you notice other symptoms such as fussiness, difficulty feeding, or if the blisters appear to be spreading, it would be prudent to consult your pediatrician for an evaluation.

In terms of management, if the blisters are indeed milk blisters, you can help by ensuring that your baby's feeding technique is optimal to minimize friction. Keeping the area clean and dry can also promote healing. If you suspect an allergic reaction or if the blisters persist or worsen, it is essential to seek medical advice. Your pediatrician may recommend a topical treatment or further evaluation to rule out any underlying conditions.

In summary, while lip blisters in infants can be concerning, they are often benign and related to feeding practices or mild reactions to milk. Close observation and consultation with your pediatrician will help determine the best course of action for your baby. If the blisters do not improve or if you have any additional concerns, do not hesitate to reach out to your healthcare provider for further guidance.

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