Extrapulmonary Tuberculosis: Severity and Treatment Options - Pulmonology

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Extrapulmonary tuberculosis


I would like to ask a question on behalf of my grandmother.
She has been hospitalized since September 7 and has been diagnosed with extrapulmonary tuberculosis, which the doctor said is located around the heart.
Previously, she also had a problem with pericardial effusion, but that has since resolved.
Now, she is facing the issue of extrapulmonary tuberculosis.
The doctor is currently using medication and drainage (according to what my cousin said).
I would like to know if extrapulmonary tuberculosis is a serious condition.
Since I have only visited my grandmother and have not spoken with the attending physician, I would like to know if there is a possibility of recovery.

Nick, 70~79 year old female. Ask Date: 2008/09/28

Dr. Qu Changke reply Pulmonology


Nick: Extrapulmonary tuberculosis refers to tuberculosis infections that occur outside the lungs.
Based on your description, your grandmother likely has pericardial tuberculosis, which has led to pericardial effusion.
Tuberculosis infections generally require treatment for at least six months and are curable.
However, tuberculosis remains the eleventh leading cause of death across various counties in Taiwan, with some counties even ranking it as the tenth leading cause of death.
Therefore, its severity should not be underestimated.

Reply Date: 2008/09/28

More Info


Extrapulmonary tuberculosis (EPTB) is a form of tuberculosis (TB) that occurs outside the lungs, and it can affect various organs, including the lymph nodes, pleura, bones, kidneys, and even the heart. In your grandmother's case, it appears she has developed pericardial tuberculosis, which is an infection of the pericardium (the membrane surrounding the heart). This condition can be serious, especially if it leads to complications such as pericardial effusion (fluid accumulation around the heart), which she has experienced in the past.

The severity of extrapulmonary tuberculosis can vary significantly depending on the location of the infection, the extent of the disease, and the patient's overall health. In general, EPTB can be more challenging to diagnose and treat than pulmonary tuberculosis because the symptoms may be less specific and can mimic other conditions. However, it is important to note that EPTB is treatable, and many patients can achieve a full recovery with appropriate medical intervention.

The treatment for extrapulmonary tuberculosis typically involves a combination of anti-tuberculous medications, similar to those used for pulmonary TB. The standard treatment regimen usually lasts for at least six months, but it may be extended based on the severity of the disease and the patient's response to therapy. In your grandmother's case, the use of medication and drainage (as mentioned by your cousin) suggests that her medical team is actively managing her condition.

Regarding the prognosis, while extrapulmonary tuberculosis can be serious, it is generally considered curable with proper treatment. The key factors influencing the prognosis include the patient's overall health, the presence of any underlying conditions, and how well the patient responds to treatment. It is crucial for your grandmother to adhere to the prescribed treatment regimen and attend regular follow-up appointments to monitor her progress.

In terms of the potential for complications, if left untreated, extrapulmonary tuberculosis can lead to significant health issues, including chronic pain, organ dysfunction, and in severe cases, it can be life-threatening. Therefore, it is essential to take her condition seriously and ensure she receives the necessary medical care.

If you have concerns about her treatment plan or prognosis, it would be beneficial to have a conversation with her healthcare provider. They can provide more detailed information about her specific case, including the expected duration of treatment, potential side effects of medications, and any lifestyle modifications that may support her recovery.

In summary, while extrapulmonary tuberculosis can be a serious condition, it is treatable, and many patients recover fully with appropriate medical care. Your grandmother's healthcare team is best positioned to provide guidance tailored to her specific situation, so maintaining open communication with them will be vital in navigating her treatment journey.

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