ENT Symptoms in Patients with Ankylosing Spondylitis - Otolaryngology

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I forgot to provide some medical history.
I am a patient with ankylosing spondylitis complicated by uveitis, and I also have hereditary urticaria.
My allergen is dust mites (moderate level).
I have anemia due to low hemoglobin levels, which are approximately between 9 and 10.
Recently, I have experienced an unusual symptom of suddenly feeling very cold.
I am studying in Kaohsiung, and my body temperature is slightly elevated, around 36.5 to 37 degrees Celsius.
My last cold was a week ago (and I have recovered).

cindy, 20~29 year old female. Ask Date: 2008/12/20

Dr. Hu Kexin reply Otolaryngology


Hello: The protrusion between your left front tooth and the adjacent tooth may not necessarily be related to the presence of mucus.
If the mucus appears with blood, you should consult an otolaryngologist for a detailed examination to identify the cause.

Reply Date: 2008/12/20

More Info


Understanding ENT (Ear, Nose, and Throat) symptoms in patients with Ankylosing Spondylitis (AS) can be quite complex, especially when considering the various comorbidities and symptoms that may arise from this condition. Ankylosing Spondylitis is a type of inflammatory arthritis that primarily affects the spine and the sacroiliac joints in the pelvis. However, it can also have systemic effects, leading to a variety of symptoms beyond musculoskeletal pain.

In your case, you mentioned having uveitis (inflammation of the eye) and hereditary urticaria (hives), along with a history of anemia. The presence of these conditions can complicate the clinical picture. Patients with AS may experience symptoms related to the ENT system due to several factors, including inflammation, immune system dysregulation, and even medication side effects.


ENT Symptoms in Ankylosing Spondylitis
1. Eustachian Tube Dysfunction: Patients with AS may experience Eustachian tube dysfunction, leading to a sensation of fullness in the ears, hearing difficulties, or even ear pain. This can be exacerbated by inflammation or allergies, such as your sensitivity to dust mites.

2. Sinusitis: Chronic inflammation can lead to sinusitis, which may present with nasal congestion, facial pain, and pressure. Given your history of allergies, you may be more susceptible to sinus infections.

3. Throat Symptoms: Some patients report a sore throat or difficulty swallowing, which can be related to inflammation in the throat or esophagus. This may also be influenced by medications used to manage AS, such as non-steroidal anti-inflammatory drugs (NSAIDs), which can cause gastrointestinal irritation.

4. Hearing Loss: While not common, some patients with AS may experience sensorineural hearing loss due to inflammatory changes affecting the inner ear structures.


Anemia and Its Implications
Your reported hemoglobin levels of 9-10 g/dL indicate anemia, which can lead to fatigue, weakness, and increased sensitivity to cold. Anemia can also exacerbate the perception of other symptoms, making it crucial to address this issue. The cold sensation you described could be related to anemia, as reduced hemoglobin levels can impair oxygen delivery to tissues, leading to a feeling of coldness, especially in extremities.


Management and Recommendations
1. Regular Monitoring: It is essential to regularly monitor your hemoglobin levels and overall blood counts, especially given your history of anemia. Addressing the underlying cause of your anemia is crucial, whether it be due to nutritional deficiencies, chronic disease, or other factors.

2. Allergy Management: Since you have a known allergy to dust mites, consider implementing measures to reduce exposure, such as using air purifiers, hypoallergenic bedding, and regular cleaning to minimize dust accumulation.

3. ENT Evaluation: If you experience persistent ENT symptoms, it may be beneficial to consult an ENT specialist. They can assess for any underlying conditions, such as sinusitis or Eustachian tube dysfunction, and recommend appropriate treatments.

4. Medication Review: Discuss your current medications with your healthcare provider to ensure that they are not contributing to your symptoms. Some medications can have side effects that impact the ENT system.

5. Lifestyle Modifications: Maintaining a healthy lifestyle, including a balanced diet rich in iron and vitamins, can help manage anemia and improve overall health. Regular exercise, as tolerated, can also help improve circulation and reduce stiffness associated with AS.

In summary, while Ankylosing Spondylitis primarily affects the spine and joints, it can have systemic effects that may lead to ENT symptoms. Given your complex medical history, a multidisciplinary approach involving your rheumatologist, hematologist, and ENT specialist may provide the best outcomes for managing your symptoms and improving your quality of life.

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