Medication Concerns in Parkinson's Disease: Symptoms and Stroke Risks - Neurology

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Medication Issues in Parkinson's Disease


My father has hypertension and experiences tremors.
A physician in Hsinchu, Dr.
Chou Ping-Chen, prescribed Parkinson's medication for him.
He has been taking it for nearly two weeks and has experienced drowsiness and dizziness.
However, on Sunday morning, his blood pressure rose to 200, and although he stopped taking the medication during the day, his blood pressure returned to normal, but the dizziness persists.
Could this be a side effect of the medication? I suspect my father may have had a stroke.
Does he need to seek emergency medical attention? Are there any diagnostic tools available to check for a stroke? I would like to take my father for a private examination to avoid any delay in treatment.
Thank you!

Tracy Chen, 40~49 year old female. Ask Date: 2009/01/05

Dr. Gao Chunde reply Neurology


The diagnosis of a stroke is not determined by unstable blood pressure or dizziness symptoms, but rather by the presence of neurological deficits assessed through a professional physician's interview and neurological examination.
As for imaging studies, magnetic resonance angiography (MRA) provides the clearest results in advanced health screenings.
However, if a physician evaluates the situation and suspects a stroke, health insurance can cover this examination, so there is no need to incur unnecessary expenses.
If one opts for out-of-pocket imaging studies and discovers some suspicious lesions, it is essential to return to a specialist for an analysis of their clinical significance.
Regarding medication, physicians can also discern whether symptoms are side effects of drugs and may suggest or adjust the treatment plan accordingly.

Reply Date: 2009/01/05

More Info


Parkinson's disease (PD) is a progressive neurodegenerative disorder primarily affecting movement. It is characterized by a range of motor symptoms, including tremors, rigidity, bradykinesia (slowness of movement), and postural instability. The disease is caused by the degeneration of dopamine-producing neurons in the substantia nigra, a part of the brain that plays a crucial role in coordinating movement. The exact etiology of Parkinson's disease remains unclear, but it is believed to involve a combination of genetic predispositions and environmental factors.

In terms of prevalence, Parkinson's disease affects approximately 1% of the population over the age of 60, with the incidence increasing with age. It is more common in men than in women, and the average onset age is around 60 years. As the global population ages, the number of individuals diagnosed with Parkinson's is expected to rise.

Treatment for Parkinson's disease primarily focuses on alleviating symptoms, as there is currently no cure. The most common pharmacological treatment involves the use of levodopa, often combined with carbidopa (as in Sinemet), which helps to replenish dopamine levels in the brain. Other medications include dopamine agonists, MAO-B inhibitors, and anticholinergics, each with specific roles in managing symptoms. Non-pharmacological approaches, such as physical therapy, occupational therapy, and speech therapy, are also essential components of comprehensive care.

Regarding the social and psychological impacts of Parkinson's disease, it can significantly affect the patient's quality of life. Patients may experience changes in their physical abilities, leading to difficulties in performing daily activities and increased dependence on caregivers. The progressive nature of the disease can lead to feelings of frustration, anxiety, and depression. Social interactions may diminish as patients withdraw due to embarrassment over their symptoms or fear of falling. Family dynamics can also be affected, as caregivers may experience stress and burnout.

Now, addressing your specific concerns about your father's situation: the symptoms of drowsiness and dizziness he is experiencing after starting Parkinson's medication could indeed be side effects of the medication. Medications used to treat Parkinson's can sometimes lead to orthostatic hypotension (a drop in blood pressure upon standing), which may explain the dizziness, especially if he has a history of high blood pressure. The sudden spike in blood pressure you mentioned could also be a response to stress or pain, or it might indicate an underlying issue that needs to be addressed.

Given your father's symptoms, it is crucial to consult a healthcare professional promptly. While dizziness and drowsiness can be side effects of medication, they can also be indicative of more serious conditions, such as a stroke. Stroke symptoms can include sudden weakness, confusion, difficulty speaking, and severe headache. If you suspect a stroke, it is essential to seek emergency medical attention immediately.

In terms of diagnostic tools for stroke, imaging studies such as a CT scan or MRI are commonly used to identify any brain abnormalities, including ischemic or hemorrhagic strokes. If your father is experiencing concerning symptoms, it is advisable to have him evaluated by a healthcare provider who can determine the need for imaging studies and further management.

In summary, while your father's symptoms may be related to medication side effects, they could also indicate a more serious condition. It is essential to seek medical advice promptly to ensure appropriate evaluation and treatment.

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