Persistent Abdominal Pain: Insights on Ulcers and Stress Factors - Gastroenterology and Hepatology

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Mild pain in the abdominal area and epigastrium?


Dear Doctor,
I have been experiencing mild pain in my abdomen and epigastric area for the past six months.
Two gastroscopies have revealed the presence of a gastric ulcer and gastroesophageal reflux disease (GERD).
The physicians have prescribed proton pump inhibitors (PPIs) for treatment, and I am currently on a strong PPI regimen.
However, despite taking the medication for about four months, I have not seen any improvement or healing.
The doctor has suggested scheduling an abdominal CT scan for a thorough examination.

Could you please advise which diagnostic method is more accurate: gastroscopy with biopsy or a CT scan? Additionally, could psychological stress (from family and work) contribute to the poor healing of my gastric ulcer and GERD? I am concerned that there may be other underlying health issues.
Thank you.

kevin, 30~39 year old female. Ask Date: 2009/02/23

Dr. Chen Shidian reply Gastroenterology and Hepatology


Hello Mr.
Kevin: PPIs can treat gastric ulcers and reflux, but there may be a recurrence after discontinuation (which is different from the definition of ineffectiveness during treatment).
A CT scan is used to examine organs other than the stomach, so the objectives are different.
Additionally, a 24-hour gastric acid measurement can be conducted while on medication.
Changhua Hospital cares about your health.
Chen Shidian

Reply Date: 2009/02/23

More Info


Dear Patient,
Thank you for reaching out with your concerns regarding your persistent abdominal pain, particularly in relation to your diagnosed conditions of gastric ulcers and gastroesophageal reflux disease (GERD). It’s understandable to feel anxious about ongoing symptoms, especially when they have persisted for six months despite treatment. Let’s break down your questions and concerns.


Understanding Your Condition
Gastric ulcers, which are sores on the lining of the stomach, and GERD, where stomach acid frequently flows back into the esophagus, can indeed cause significant discomfort and pain. The treatment you are receiving, particularly with proton pump inhibitors (PPIs), is standard and effective for reducing stomach acid production, which helps in healing ulcers and alleviating GERD symptoms. However, the fact that you have not seen improvement after four months of treatment raises some important considerations.


Diagnostic Accuracy
Regarding the accuracy of diagnostic tests, both endoscopy (gastroscopy) and CT scans serve different purposes:
1. Endoscopy: This procedure allows direct visualization of the esophagus, stomach, and duodenum. It is highly accurate for diagnosing ulcers and can also allow for biopsy, which can rule out malignancy or other conditions. It is considered the gold standard for evaluating upper gastrointestinal issues.

2. CT Scan: While a CT scan can provide detailed images of the abdominal organs and can help identify complications related to ulcers (like perforation or abscess), it is not as effective as endoscopy for directly visualizing the mucosal lining of the stomach and esophagus.

In summary, endoscopy is generally more accurate for diagnosing ulcers and related conditions, while a CT scan can be useful for assessing complications or other abdominal issues.


The Role of Stress
Your concern about the impact of psychological stress on your condition is valid. Chronic stress, particularly from family or work-related pressures, can exacerbate gastrointestinal issues. Stress can lead to increased acid production, affect gut motility, and alter the gut microbiome, all of which can contribute to the persistence of ulcers and GERD symptoms.
Moreover, anxiety can heighten your perception of pain, making it feel more intense. It’s crucial to address both the physical and psychological aspects of your health. Techniques such as cognitive-behavioral therapy (CBT), mindfulness, and stress management strategies can be beneficial in managing anxiety and may indirectly improve your gastrointestinal symptoms.


Next Steps
Given your ongoing symptoms and the lack of improvement, it is wise to follow through with your physician's recommendation for a CT scan. This will help rule out any other potential issues that might be contributing to your discomfort. Additionally, consider discussing your psychological stressors with your healthcare provider. They may recommend a multidisciplinary approach that includes both medical treatment for your ulcers and support for managing stress and anxiety.

In conclusion, while PPIs are effective, they may not be sufficient alone if there are underlying stress factors or other complications. A comprehensive approach that addresses both your physical and mental health will likely yield the best outcomes. Please continue to communicate openly with your healthcare team about your symptoms and concerns.

Wishing you the best in your journey toward recovery.

Sincerely,
Doctor Q&A Teams

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