Acute
Hello Dr.
Ke,
I would like to ask about my father, a 72-year-old male, who is suffering from pneumonia complicated by ARDS.
His current condition is as follows: the cause of pneumonia is unknown, with reports indicating the presence of Gram-positive bacteria.
He is being treated with vancomycin and steroids in the ICU.
He has been intubated for 12 days, with high PEEP settings (approximately 11-14), oxygen levels at 45-55%, and SaO2 at 90-92%.
Sedatives and neuromuscular blockers are being used.
The physician has stated that the X-ray shows severe fibrosis and that we can only wait for the disease to progress.
I would like to inquire about the following:
1.
The physician mentioned that the disease progression has stagnated and that the severe X-ray fibrosis may indicate that he cannot be weaned off the ventilator.
What does this mean? Is there a possibility for improvement?
2.
With oxygen levels at 55% and the hospital lacking nitric oxide treatment equipment, will this affect the course of the disease?
3.
If there are no other organ dysfunctions, is there a chance for improvement? Typically, does the course of the disease require more than a month or even longer? Does the risk decrease over time?
4.
Regarding nutritional support, aside from self-paid albumin, can we consider products like Ensure or others?
Thank you very much!
nurse, 30~39 year old female. Ask Date: 2009/03/24
Dr. Ke Zhengchang reply Pulmonology
Hello: Based on your description, your father's condition is quite severe, with pneumonia complicated by ARDS, poor gas exchange, and a generally unfavorable prognosis.
Once the lungs progress to fibrosis, the chance of survival and weaning off the ventilator is only 10-20%.
Inhaled nitric oxide is only available at medical centers and can only temporarily improve blood oxygen saturation; it does not help with prognosis or survival rates.
If there is only respiratory failure while other organs such as the heart, kidneys, and liver are functioning normally, there is a chance for improvement, but continuous treatment for at least 1-2 months is necessary.
Nutritional support should primarily focus on increasing enteral feeding, such as with products like Pulmonary Care or Nutrison, requiring approximately 2000 calories per day.
Albumin supplementation is insufficient for nutritional support and should only be used temporarily for shock and severe pulmonary edema; it cannot be used continuously for nutritional supplementation.
Reply Date: 2009/03/24
More Info
Understanding ARDS (Acute Respiratory Distress Syndrome) in the context of pneumonia can be quite complex, especially when dealing with a patient who is critically ill. Your father's situation, being a 72-year-old male with pneumonia complicated by ARDS, requires careful consideration of various factors that can influence his recovery and overall prognosis.
1. Understanding the Implications of Severe Fibrosis: When the physician mentions that the X-ray shows severe fibrosis and that the disease progression has stagnated, it indicates that the lung tissue has undergone significant scarring. This scarring can severely impair lung function and may limit the ability to wean off mechanical ventilation. While it is possible for some patients to improve, especially if the underlying cause of ARDS is addressed, the presence of severe fibrosis often suggests a poorer prognosis. Recovery from ARDS can take weeks to months, and in some cases, patients may not fully recover lung function.
2. Impact of High Oxygen Levels and Lack of Nitric Oxide Therapy: The use of high levels of supplemental oxygen (55% in your father's case) is often necessary in ARDS to maintain adequate oxygen saturation levels. However, prolonged exposure to high oxygen concentrations can lead to oxygen toxicity and further lung injury. The absence of nitric oxide therapy, which can help improve oxygenation by dilating pulmonary blood vessels, may limit treatment options. While it may not directly affect the course of the disease, the lack of this therapy could mean that alternative methods to improve oxygenation are not being utilized.
3. Potential for Recovery and Duration of Illness: If there are no other organ failures, there is still a possibility for improvement, although it may be slow. The duration of ARDS can vary significantly among patients; some may take over a month to show signs of improvement, while others may take much longer. The "danger period" typically decreases as the patient stabilizes, but this is contingent upon ongoing monitoring and management of any complications that may arise.
4. Nutritional Support: Nutritional support is crucial in critically ill patients, especially those on mechanical ventilation. While albumin can be beneficial for maintaining oncotic pressure and supporting fluid balance, other nutritional supplements like specialized formulas (e.g., Ensure or similar products) can provide essential nutrients that support recovery. It is important to consult with a dietitian to tailor nutritional support to your father's specific needs, considering his medical condition and any dietary restrictions.
In summary, your father's situation is serious, and while there are challenges ahead, ongoing medical care and supportive therapies can make a difference. It is essential to maintain open communication with the healthcare team, ask questions about his treatment plan, and understand the potential outcomes. Each patient's journey through ARDS is unique, and while the road may be long, there is hope for improvement with appropriate care and support.
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