Can Weight Training Affect DHT Levels in Baldness?

Q: Can Weight Training Affect DHT Levels in Baldness?

Hello： The ingredients of Ropay and Shiyur Tong are different; the former targets type II 5α-reductase and acts as an inhibitor; Avodart (Dutasteride) is an inhibitor of both type I and type II 5α-reductase. <br>The latter has a stronger inhibitory effect on benign prostatic hype

Can individuals with baldness engage in strength training?

Rovatinex can inhibit type I 5α-reductase, preventing testosterone from being converted into DHT.
A senior from the sports team mentioned that exercise can increase testosterone levels, and more fitness training is needed because muscle building relies on testosterone.
So, I would like to ask the doctor, does frequent exercise or working out lead to the production of more DHT? Or does type I 5α-reductase only convert a fixed amount of testosterone into DHT? Additionally, does the doctor recommend taking Avodart (dutasteride) for its diuretic properties? I read online that it can inhibit both type I and type II 5α-reductase, while Rovatinex can only reduce DHT levels by about 70%, whereas Avodart can reduce it by up to 95%.
However, I rarely hear about people taking it.

A-Zhe, 20~29 year old female. Ask Date: 2009/04/24

Dr. Zhang Zhibo reply Dermatology

Hello: The ingredients of Ropay and Shiyur Tong are different; the former targets type II 5α-reductase and acts as an inhibitor; Avodart (Dutasteride) is an inhibitor of both type I and type II 5α-reductase.
The latter has a stronger inhibitory effect on benign prostatic hyperplasia; currently, there is no indication for use in male pattern baldness; however, future research may emerge, as pharmaceutical companies would likely want to explore more indications for their drugs! Does exercising or working out synthesize more DHT? There are reports of administering exogenous androgens to athletes; of course, their DHT levels would also increase.
Androgens contribute to muscle growth, but does exercise increase androgen levels? The primary sites of androgen production are the testes and adrenal glands in males, and the adrenal glands and ovaries in females; physiologically, the focus is on reproductive functions.
The question of whether "exercise or working out synthesizes more DHT" requires further investigation into relevant studies!

Reply Date: 2009/04/24

More Info

When discussing the relationship between weight training, dihydrotestosterone (DHT) levels, and baldness, it's essential to understand the underlying biology and how these factors interact. DHT is a potent androgen derived from testosterone through the action of the enzyme 5-alpha reductase. This conversion process is significant because DHT is known to play a crucial role in androgenetic alopecia, commonly referred to as male or female pattern baldness.

Weight training and exercise, in general, can influence hormone levels in the body. Engaging in regular resistance training has been shown to increase testosterone levels temporarily. However, the relationship between testosterone and DHT is complex. While higher testosterone levels can lead to increased DHT production, the extent of this increase is influenced by individual factors such as genetics, age, and overall hormonal balance.

Regarding your question about whether frequent exercise or weight training leads to more DHT synthesis, it is important to note that the conversion of testosterone to DHT is not solely dependent on testosterone levels. The activity of the 5-alpha reductase enzyme is also a critical factor. Therefore, even if testosterone levels rise due to weight training, it does not necessarily mean that DHT levels will increase proportionately. The body has regulatory mechanisms that can modulate the activity of this enzyme based on various physiological conditions.

As for the use of medications like Avodart (dutasteride) and Proscar (finasteride), these drugs are designed to inhibit the action of 5-alpha reductase, thereby reducing DHT levels in the body. Avodart is known to inhibit both type I and type II isoforms of the enzyme, potentially leading to a more significant reduction in DHT levels compared to finasteride, which primarily targets type II. This reduction in DHT can be beneficial for individuals experiencing hair loss due to androgenetic alopecia.

If you are considering using these medications, it is crucial to consult with a healthcare professional. They can provide personalized advice based on your medical history, current health status, and specific concerns regarding hair loss and hormone levels. Additionally, while these medications can be effective in reducing DHT levels, they may also come with side effects, and their long-term safety profile should be discussed with a doctor.

In summary, while weight training can influence testosterone levels, the relationship with DHT is multifaceted and not solely dependent on exercise. If you are concerned about hair loss and its connection to hormone levels, it is advisable to seek guidance from a medical professional who can help you navigate your options, including lifestyle changes, exercise regimens, and potential pharmacological treatments.

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