Recurrent Miscarriage: Causes, Treatments, and Expert Guidance - Obstetrics and Gynecology

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Habitual miscarriage


Hello, I would like to inquire about habitual miscarriage.
I already have two children, but my subsequent pregnancies have resulted in bleeding around three months, requiring bed rest.
In the first instance, I experienced premature rupture of membranes and miscarried naturally after about a week of bed rest.
The second time, I also had bleeding and was hospitalized for bed rest, but after just one day, I was unable to maintain the pregnancy, leading to premature rupture of membranes again.
The doctor suspects that there may be cervical incompetence, but it's not certain.
After the second miscarriage, we underwent chromosomal testing at the hospital, and both my partner and I had no issues.
Now that I am pregnant again, what steps can I take to avoid another miscarriage? Is immunotherapy (injection of third-party white blood cells) effective? Could you please tell me who the specialist in Kaohsiung is that focuses on habitual miscarriage? I would appreciate Dr.
Wu addressing my concerns.
Thank you.

Guo, 30~39 year old female. Ask Date: 2009/05/27

Dr. Chen Changfu reply Obstetrics and Gynecology


Sorry, please correct Dr.
Wu's email address.

Reply Date: 2009/05/27

More Info


Recurrent miscarriage, often defined as the loss of three or more consecutive pregnancies, can be a distressing experience for couples trying to conceive. Understanding the potential causes and exploring treatment options is crucial for those affected.
There are several factors that can contribute to recurrent miscarriages. These include anatomical issues, such as uterine abnormalities (like a septate uterus), cervical insufficiency, and hormonal imbalances. Genetic factors can also play a role; chromosomal abnormalities in the embryo are a common cause of miscarriage, although you mentioned that both you and your partner have undergone chromosomal testing with no issues found.
Another area to consider is autoimmune disorders, where the body’s immune system may mistakenly attack the pregnancy. Conditions such as antiphospholipid syndrome (APS) can lead to recurrent pregnancy loss. In your case, you mentioned undergoing immunotherapy with third-party white blood cells, which is an approach some practitioners use to modulate the immune response. However, the efficacy of such treatments can vary, and it is essential to discuss this with a specialist who understands the nuances of recurrent miscarriage.

In terms of management, if cervical incompetence is suspected, a cervical cerclage may be recommended. This surgical procedure involves placing stitches in the cervix to help keep it closed during pregnancy. Additionally, progesterone supplementation has been shown to be beneficial in some cases, particularly if there is a history of luteal phase defects.

Lifestyle factors should also be considered. Maintaining a healthy weight, managing chronic conditions (like diabetes or hypertension), and avoiding smoking and excessive alcohol consumption can all contribute positively to pregnancy outcomes.
As for your specific situation, since you have already experienced two miscarriages and are currently pregnant, it is essential to have close monitoring by a healthcare provider. Regular ultrasounds and check-ups can help assess the health of the pregnancy and identify any potential issues early on.
Regarding your inquiry about specialists in Kaohsiung who focus on recurrent miscarriage, I recommend seeking out a reproductive endocrinologist or a maternal-fetal medicine specialist. These professionals often have extensive experience in managing complex cases of recurrent pregnancy loss. They can provide tailored advice and treatment options based on your unique medical history and current situation.

In summary, recurrent miscarriage can stem from a variety of causes, and a comprehensive approach to diagnosis and treatment is essential. Collaborating with a specialist who understands the complexities of recurrent miscarriage will provide you with the best chance of a successful pregnancy. It’s important to remain hopeful and proactive in seeking the care you need.

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