Numbness in the hands and feet caused by chemotherapy?
Hello, Doctor: I have been diagnosed with salivary gland cancer and have undergone twelve cycles of chemotherapy and thirty-five sessions of radiation therapy.
During the sixth cycle of chemotherapy, I was hospitalized due to nerve numbness.
Taking B vitamins did not help.
At that time, the attending physician prescribed a blue capsule, which completely alleviated the numbness and the electric sensation running from head to toe after just one dose.
What medication could that have been? It has been six months since completing radiation therapy, and I still experience numbness and lack of sensation in my hands and feet.
What medication could improve this? The B vitamins have not been effective.
Please help me with this.
Thank you.
Zhenzhen, 40~49 year old female. Ask Date: 2009/08/02
Dr. Ye Boshou reply Neurology
We apologize, but it is not possible to determine whether the medication is related.
Please first confirm if there is neuropathy (you may want to start with a neurology examination).
If it is indeed caused by chemotherapy drugs, it may take a long time to improve.
Reply Date: 2009/08/02
More Info
Managing nerve tingling and numbness after chemotherapy can be a challenging aspect of recovery for many cancer patients. Chemotherapy, while effective in treating cancer, can lead to a range of side effects, including peripheral neuropathy, which is characterized by tingling, numbness, and pain in the hands and feet. This condition can significantly affect a patient's quality of life, making it essential to explore effective treatment options.
In your case, it seems that you experienced significant nerve-related symptoms during your chemotherapy treatment for salivary gland cancer. The fact that you were prescribed a blue capsule that provided immediate relief suggests that it might have been a medication specifically aimed at managing neuropathic pain or discomfort. Common medications used for this purpose include gabapentin (Neurontin) and pregabalin (Lyrica), both of which are anticonvulsants that have been found to be effective in treating nerve pain. These medications work by stabilizing electrical activity in the nervous system and can help alleviate the sensations of tingling and numbness.
Since you mentioned that B vitamins, particularly B12, did not provide relief, it is important to note that while B vitamins are often recommended for nerve health, their effectiveness can vary from person to person. In some cases, the nerve damage caused by chemotherapy may not respond to vitamin supplementation alone. It is also worth considering that the absorption of these vitamins can be affected by various factors, including the presence of other medical conditions or medications.
If you are still experiencing numbness and tingling six months after completing radiation therapy, it is crucial to consult with your healthcare provider. They may recommend further evaluations, such as nerve conduction studies or electromyography (EMG), to assess the extent of nerve damage and to rule out other potential causes of your symptoms. Based on the findings, your doctor may suggest alternative treatments, which could include:
1. Medications: As previously mentioned, gabapentin or pregabalin may be prescribed. Other options include duloxetine (Cymbalta), which is an antidepressant that has been shown to help with nerve pain.
2. Physical Therapy: Engaging in physical therapy can help improve strength and coordination, which may alleviate some of the symptoms associated with nerve damage.
3. Transcutaneous Electrical Nerve Stimulation (TENS): This therapy involves using low-voltage electrical currents to relieve pain and may help with symptoms of neuropathy.
4. Topical Treatments: Creams containing capsaicin or lidocaine may provide localized relief from nerve pain.
5. Lifestyle Modifications: Regular exercise, a balanced diet, and proper hydration can support overall nerve health. Additionally, avoiding alcohol and managing blood sugar levels (if diabetic) can be beneficial.
6. Alternative Therapies: Some patients find relief through acupuncture, massage therapy, or other complementary approaches.
7. Nutritional Support: In addition to B vitamins, ensuring adequate intake of antioxidants and omega-3 fatty acids may support nerve health.
It is essential to have an open dialogue with your healthcare team about your symptoms and treatment options. They can help tailor a management plan that addresses your specific needs and improves your quality of life. Remember, recovery from chemotherapy can take time, and patience is key as you navigate this process.
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