Why Does Eye Drop Application Cause Pain and Redness? - Ophthalmology

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Instilling eye drops may cause a stinging sensation in the eyes?


Dear Dr.
Hu,
I apologize for bothering you again with a question.
Every night, I apply Chloramphenicol eye drops to both of my eyes.
Since this eye drop needs to be refrigerated, I let it sit out for half an hour to warm up before applying it, as I don’t want it to be too cold when I put it in my eyes.
Recently, I have been experiencing a sharp pain in the inner corners of both eyes when applying the drops, and my eyes become red, especially the left eye (which has undergone two retinal reattachment surgeries using scleral buckle technique).
I would like to ask you:
1.
Could letting the eye drops warm up cause the stinging sensation when I apply them?
2.
Should I discuss with my doctor the possibility of switching to a different eye drop?
3.
Does frequent stinging and redness from the eye drops affect the retina?
Thank you for your assistance.

Xiao Lai, 30~39 year old female. Ask Date: 2009/09/03

Dr. Hu Yusheng reply Ophthalmology


Hello: Please stop taking the medication and return to your physician's office as soon as possible for further discussion.
(Note) After opening, eye drops should be stored in a cool place unless otherwise instructed, and should be used within one month.
Wishing you peace and good health.

Reply Date: 2009/09/03

More Info


When it comes to the discomfort you are experiencing after applying eye drops, particularly Chloramphenicol, there are several factors to consider that could explain the pain and redness you are encountering.

1. Temperature of the Eye Drops: You mentioned that you allow the eye drops to warm up after taking them out of the refrigerator. While it's generally advisable to avoid applying very cold drops directly to the eye, allowing them to sit out for about half an hour should not typically cause significant discomfort. However, if the drops are still too cold, it might lead to a brief sensation of discomfort upon application. It is best to ensure that the drops are at room temperature before applying them.

2. Composition of the Eye Drops: Chloramphenicol is an antibiotic used to treat bacterial infections of the eye. While effective, it can cause irritation in some individuals, especially if there is a sensitivity to the preservative or the active ingredient itself. If you notice consistent pain and redness after using these drops, it may be worth discussing with your doctor the possibility of switching to a different formulation, perhaps one that is preservative-free, as preservatives can sometimes exacerbate irritation.

3. Underlying Eye Conditions: Given your history of retinal surgery, it is crucial to consider that any discomfort, redness, or pain could be related to your previous eye conditions or surgeries. The fact that you have undergone two retinal surgeries may mean that your eyes are more sensitive than usual. Post-surgical eyes can sometimes react differently to medications, including eye drops. If the pain is localized and particularly pronounced in the left eye, it may be worth investigating further to ensure there are no complications related to your surgeries.

4. Impact on the Retina: Frequent application of eye drops that cause pain and redness should be monitored closely. While mild irritation from eye drops typically does not directly affect the retina, persistent inflammation or discomfort could lead to changes in how you use your eyes, potentially leading to strain or other issues. If you are experiencing significant discomfort, it is advisable to consult with your ophthalmologist to ensure that there are no underlying issues that could affect your vision or the health of your retina.

5. Consultation with Your Doctor: Given your symptoms, it would be prudent to discuss these issues with your eye care provider. They may recommend a different type of eye drop or a different treatment regimen that could alleviate your discomfort. Additionally, they might want to perform a thorough examination to rule out any complications from your previous surgeries or other underlying conditions.

In summary, while the pain and redness you are experiencing after applying eye drops could be due to several factors, including the temperature of the drops, the formulation of the medication, and your unique medical history, it is essential to consult with your healthcare provider. They can provide tailored advice and ensure that your eye health remains a priority, especially considering your surgical history. Regular follow-ups and open communication with your ophthalmologist will help manage any discomfort and maintain your vision health effectively.

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