Can LP33 Probiotics Help with Allergic Rhinitis Symptoms? - Otolaryngology

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Hello Doctor: I have allergic rhinitis and often experience a runny nose due to temperature changes.
Recently, I've seen advertisements claiming that LP33 probiotics can improve allergic rhinitis.
I consulted with an ENT specialist at a clinic, and some said it could be taken, while others mentioned it is more beneficial for those with asthma.
Could you please clarify whether LP33 is helpful or not?

Billy, 20~29 year old female. Ask Date: 2009/09/25

Dr. Hu Kexin reply Otolaryngology


Hello: Currently, there is insufficient medical evidence to show that LP33 can improve symptoms in all patients with allergic rhinitis.

Reply Date: 2009/09/25

More Info


Allergic rhinitis, commonly known as hay fever, is an inflammatory condition affecting the nasal passages, often triggered by allergens such as pollen, dust mites, or pet dander. Symptoms typically include sneezing, runny or stuffy nose, itchy eyes, and postnasal drip. Managing these symptoms often involves a combination of avoidance strategies, antihistamines, nasal corticosteroids, and sometimes immunotherapy. Recently, probiotics have gained attention for their potential role in managing allergic conditions, including allergic rhinitis.

LP33 is a specific strain of probiotics, Lactobacillus plantarum LP33, which has been studied for its effects on immune modulation and inflammation. Some research suggests that certain probiotic strains can help balance the gut microbiome, which in turn may influence the immune system's response to allergens. The theory is that a healthy gut microbiome can enhance the body's ability to tolerate allergens and reduce the severity of allergic reactions.

While some studies have indicated that probiotics, including LP33, may have a beneficial effect on allergic rhinitis symptoms, the evidence is not yet conclusive. The results can vary significantly depending on the individual, the specific probiotic strain used, and the dosage. Some patients report improvements in their symptoms, while others may not notice any significant change.
It's also important to note that while probiotics can be a helpful adjunct to traditional treatments, they should not replace standard therapies prescribed by healthcare professionals. For individuals with allergic rhinitis, the primary treatment options remain antihistamines and nasal corticosteroids, which have a well-established efficacy in managing symptoms.

Regarding the conflicting opinions from different healthcare providers, this is not uncommon in the medical field. Probiotics are still a relatively new area of research, and while some practitioners may be enthusiastic about their potential benefits, others may be more cautious, especially if they feel that the evidence is not robust enough to warrant a recommendation.

If you are considering using LP33 probiotics for your allergic rhinitis, it may be beneficial to discuss this with your healthcare provider, preferably one who is knowledgeable about both allergy management and probiotics. They can help you weigh the potential benefits against any risks and determine whether this approach is appropriate for your specific situation.

In summary, while LP33 probiotics may offer some potential benefits for managing allergic rhinitis symptoms, the evidence is still emerging. They should be viewed as a complementary approach rather than a primary treatment. Continued research is needed to fully understand the role of probiotics in allergic conditions, and it is essential to maintain open communication with your healthcare provider about all aspects of your treatment plan.

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