Hydronephrosis: Causes, Symptoms, and Treatment Options - Urology

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Renal edema issues?


The patient is eighteen years old and has been experiencing pain in the right lower abdomen and groin for the past three years.
Recently, the pain has occurred approximately once a month, severe enough to cause vomiting, with each episode lasting about 2-3 days before returning to normal.
Due to the proximity of the pain to a previous surgical site from childhood hernia repair, a local clinic physician recommended seeing a gastroenterologist.
However, consultations at a major medical center's surgery and gastroenterology departments yielded no results.
The most recent visit was to a urologist, where an ultrasound revealed severe right-sided hydronephrosis, indicating that the condition has been present for a long time.
Subsequent tests, including renal imaging, CT scans, and endoscopy, diagnosed a narrowing and obstruction at the junction of the right ureter and kidney.
The endoscopic examination was unable to pass through the obstruction.
The physician recommended an MRI (which has not yet been performed) to confirm whether renal function is above 15%.
If it is, a ureteral reconstruction surgery is planned; if not, nephrectomy is advised.
The patient inquires whether nephrectomy is absolutely necessary if renal function is below 15% and why the pain is localized to the right lower abdomen if the hydronephrosis and pain are due to ureteral obstruction, with no discomfort reported in the kidney area.

Ji, 10~19 year old female. Ask Date: 2009/12/05

Dr. Lin Hexing reply Urology


Hello, sir: Thank you for your inquiry.
I would like to respond to your question and provide the following advice: You should arrange for a nuclear medicine diuretic renal scan to assess your kidney function status.
This is a benign condition, and as long as there is some remaining function, you should not hastily consider removal.
The symptoms may not be very clear, and discomfort or pain can occur from the right flank to the right lower abdomen.
Finally, I wish you peace and happiness!

Reply Date: 2009/12/05

More Info


Hydronephrosis is a medical condition characterized by the swelling of a kidney due to a build-up of urine. This occurs when there is an obstruction in the urinary tract that prevents urine from draining properly from the kidney to the bladder. Understanding the causes, symptoms, and treatment options for hydronephrosis is crucial, especially in your case, where you have been experiencing significant discomfort and have received a diagnosis of severe right-sided hydronephrosis.


Causes of Hydronephrosis
Hydronephrosis can be caused by various factors, including:
1. Obstruction: This is the most common cause and can occur due to kidney stones, tumors, or strictures (narrowing) in the ureter or urethra. In your case, the diagnosis of a narrowing at the junction of the ureter and kidney suggests that this is the likely cause of your hydronephrosis.

2. Infection: Urinary tract infections can lead to swelling and inflammation, which may obstruct urine flow.

3. Congenital Abnormalities: Some individuals are born with structural abnormalities in their urinary tract that can lead to hydronephrosis.

4. Pregnancy: The growing uterus can exert pressure on the ureters, leading to obstruction.

5. Neurological Disorders: Conditions that affect the nerves controlling the bladder can lead to urinary retention and hydronephrosis.


Symptoms of Hydronephrosis
Symptoms can vary depending on the severity of the condition and the underlying cause. Common symptoms include:
- Flank Pain: Pain in the side or back, which may radiate to the lower abdomen or groin.

- Nausea and Vomiting: As you have experienced, severe pain can lead to nausea and vomiting.

- Changes in Urination: This may include decreased urine output, urgency, or difficulty urinating.

- Infections: Symptoms of urinary tract infections, such as fever, chills, or burning during urination, may also occur.

In your situation, the right lower abdominal pain could be attributed to the pressure and irritation caused by the hydronephrosis and the obstruction in the ureter. The kidneys themselves may not always produce pain due to their anatomical structure; instead, the discomfort can manifest in areas where the nerves are more sensitive.


Treatment Options
The treatment for hydronephrosis primarily focuses on relieving the obstruction and preserving kidney function. Here are some common approaches:
1. Observation: If the hydronephrosis is mild and not causing significant symptoms, doctors may choose to monitor the condition.

2. Medications: Pain relief and treatment of any underlying infections may be necessary.

3. Surgical Intervention: Given your diagnosis of severe hydronephrosis due to ureteral obstruction, surgical options may be required. The decision to perform a ureteral reconstruction or nephrectomy (kidney removal) depends on the kidney's function, which is assessed through imaging studies and kidney function tests.

- If your kidney function is determined to be below 15%, nephrectomy may be recommended to prevent further complications, such as infection or systemic issues related to a non-functioning kidney.

- If the kidney function is above 15%, reconstructive surgery may be performed to restore normal urine flow.


Conclusion
In summary, hydronephrosis is a serious condition that requires careful evaluation and management. The pain you are experiencing is likely related to the obstruction and pressure from the hydronephrosis. It is essential to follow up with your healthcare provider regarding the MRI results and the next steps in your treatment plan. If surgery is necessary, your healthcare team will discuss the risks and benefits with you, ensuring that you are informed and comfortable with the decisions made regarding your health. Always communicate any new symptoms or concerns with your doctor, as timely intervention can significantly impact outcomes.

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