Mild Fever and Persistent Cough: When to Seek Further Testing - Pulmonology

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mild fever


As a child, I frequently caught colds, almost having to visit the doctor every month.
However, about seven or eight years ago, I became much less sick.
But whenever I do get sick, I tend to cough severely, often taking nearly a month to recover.
After not having a cold for two years, I recently became ill again due to excessive work stress, suddenly experiencing fever and cough.
My temperature mostly hovers around 37.5°C, with a maximum of no more than 38°C.
I have tested negative for H1N1 with a rapid test, and my blood test showed a white blood cell count of 12,000.
I have been on antibiotics for over two weeks, received one injection of Kason, and underwent a Low-Dose Chest CT which showed no significant abnormalities.
However, I have still been experiencing severe coughing for about two weeks, with a dry cough that feels almost non-productive, although auscultation reveals some slight wheezing.
There have been one or two instances of coughing up white phlegm.
Just in the last couple of days, my cough symptoms have finally stopped, but I still have a mild fever, with morning and evening temperatures dropping to around 36.7°C.
I have not experienced any weight loss or loss of appetite.
I am concerned whether there might be a risk of TB infection.
Could it be that my youth and stronger immune system are preventing obvious symptoms of pulmonary tuberculosis? Should I undergo further screening? However, I do not produce sputum and feel like there is not much phlegm.
What should I do?

Lan, 20~29 year old female. Ask Date: 2010/01/18

Dr. Jian Shuntian reply Pulmonology


Hello, the chest CT scan is normal, but tuberculosis (TB) cannot be ruled out.
It is recommended to test three sputum samples.
If sputum is not available, an induced sputum procedure can be performed.
The likelihood of pulmonary tuberculosis or bronchial tuberculosis is low, so it is advised to consult a pulmonologist for further examination.
Thank you for your response.
Sincerely, Dr.
Jian Shun-Tian, Chief of Pulmonary Medicine.

Reply Date: 2010/01/18

More Info


When experiencing mild fever and persistent cough, especially after a history of frequent respiratory infections, it is essential to approach the situation with caution and awareness of potential underlying conditions. Your symptoms, including a mild fever (around 37.5°C, peaking at 38°C), persistent cough lasting about two weeks, and a history of elevated white blood cell count, suggest that you may be dealing with an infectious process or another underlying issue that requires further evaluation.

Given your recent negative H1N1 rapid test and the fact that you have been on antibiotics for over two weeks without significant improvement, it is crucial to consider other possible causes of your symptoms. The presence of a mild fever, especially when it fluctuates, can indicate that your body is still fighting an infection, which could be viral or bacterial in nature. The cough, which has transitioned from dry to slightly productive with white phlegm, further complicates the clinical picture.

While tuberculosis (TB) is a concern, especially in individuals with a history of respiratory issues, it is important to note that TB often presents with more pronounced symptoms, such as significant weight loss, night sweats, and hemoptysis (coughing up blood). However, it is not impossible for TB to present with milder symptoms, particularly in younger individuals with robust immune systems. The absence of significant weight loss or appetite changes is reassuring but does not entirely rule out the possibility of TB or other chronic infections.

In your case, the following steps are recommended:
1. Further Testing: Since you have already undergone a Low-Dose Chest CT without significant findings, consider additional tests such as a sputum culture or a TB skin test (Mantoux test) or an interferon-gamma release assay (IGRA) to rule out TB. These tests can provide more definitive answers regarding the presence of TB or other chronic infections.

2. Pulmonary Function Tests: Given your history of severe coughing and respiratory issues, pulmonary function tests may help assess your lung function and determine if there are any underlying obstructive or restrictive patterns.

3. Follow-Up with a Specialist: If your symptoms persist or worsen, it may be beneficial to consult a pulmonologist who specializes in respiratory diseases. They can provide a more comprehensive evaluation and may recommend additional imaging or tests based on their findings.

4. Monitor Symptoms: Keep a close eye on your symptoms, including any changes in cough, fever patterns, or the presence of new symptoms such as chest pain, difficulty breathing, or changes in sputum color or consistency. If you experience any of these, seek medical attention promptly.

5. Rest and Hydration: Ensure you are getting adequate rest and hydration, as these are crucial for recovery from any infection.
6. Consider Other Causes: Other potential causes of your symptoms could include viral infections (like COVID-19 or other respiratory viruses), atypical bacterial infections (such as Mycoplasma pneumonia), or even allergic reactions. Discuss these possibilities with your healthcare provider.

In summary, while your symptoms may not immediately suggest a severe condition, the persistence of mild fever and cough warrants further investigation to rule out infections such as TB or other chronic respiratory issues. It is always better to err on the side of caution and seek further testing if symptoms do not improve or if you have concerns about your health.

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