Shortness of Breath: Causes and Concerns in Chest Medicine - Pulmonology

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Why do people experience shortness of breath or difficulty breathing?


Three weeks ago, I was hospitalized for acute pyelonephritis for six days.
One night, I experienced shortness of breath, rapid heartbeat, and fever.
After receiving supplemental oxygen, I gradually felt better.
An electrocardiogram showed no issues, but my white blood cell count was over 20,000, and my blood pressure was in the 80s.
The doctor mentioned that I was close to sepsis.
I had a myomectomy, and the following night, I experienced the same shortness of breath and difficulty breathing again, with my blood pressure around 90 and no fever.
The common factor in both hospitalizations was the shortness of breath, which improved after receiving oxygen.
In the past, I only occasionally experienced a rapid heartbeat without any shortness of breath.
I am unsure what the underlying issue might be.

Gao, 20~29 year old female. Ask Date: 2002/01/21

Dr. Jian Shuntian reply Pulmonology


The first episode may have been triggered by a bacterial infection, leading to signs of sepsis.
The second episode could be due to a drop in blood pressure.
Both instances are related to blood pressure; when blood pressure decreases, tissue perfusion is insufficient, resulting in tissue hypoxia, which causes shortness of breath.
Administering oxygen can improve this condition.
It is important to assess whether the baseline blood pressure was already low, or if there are issues such as anemia or any cardiac problems.
Further evaluation by a physician is recommended.

Reply Date: 2002/01/21

More Info


Understanding shortness of breath (dyspnea) can be complex, especially when it occurs in conjunction with other medical conditions. In your case, the episodes of shortness of breath during your hospitalizations for acute pyelonephritis and subsequent surgery for uterine fibroids raise several important considerations.

Firstly, it is essential to recognize that shortness of breath can stem from various causes, including respiratory, cardiovascular, hematologic, and even psychological factors. Given your recent medical history, we can explore a few potential explanations for your symptoms.

1. Infection and Inflammation: The acute pyelonephritis you experienced could lead to systemic inflammation, which may affect your respiratory system. High white blood cell counts, as you mentioned, indicate an inflammatory response, which can sometimes lead to respiratory distress. In severe cases, infections can cause pneumonia or acute respiratory distress syndrome (ARDS), both of which can manifest as shortness of breath.

2. Fluid Overload: During hospitalization, especially with conditions like pyelonephritis, patients may receive intravenous fluids. If there is any underlying heart or kidney dysfunction, this can lead to fluid overload, resulting in pulmonary edema, which can cause significant breathing difficulties.

3. Anxiety and Stress: Hospitalization can be a stressful experience, and anxiety can exacerbate feelings of breathlessness. The sensation of not being able to breathe can trigger a panic response, leading to a cycle of anxiety and respiratory distress. This is particularly relevant if you have a history of anxiety or if the hospital environment is triggering for you.

4. Cardiovascular Factors: Although your ECG did not show any issues, it is still important to consider that heart conditions can lead to dyspnea. Conditions such as heart failure or arrhythmias can cause shortness of breath, especially if there is a sudden change in your health status. The fact that your blood pressure was low during these episodes could also suggest a cardiovascular component.

5. Pulmonary Issues: Given that you experienced shortness of breath on two separate occasions, it is crucial to rule out any pulmonary complications. Conditions such as pulmonary embolism (a blood clot in the lungs) can occur, especially in patients who have been immobile for extended periods. This condition can present with sudden onset dyspnea and may require immediate medical attention.

6. Postoperative Complications: After surgery, especially abdominal or pelvic surgery, patients can experience respiratory complications due to pain, shallow breathing, or even atelectasis (collapse of part of the lung). This can lead to feelings of breathlessness, particularly if pain management is inadequate.

Given these considerations, it is essential to follow up with your healthcare provider to discuss your symptoms in detail. They may recommend further investigations, such as imaging studies (like a chest X-ray or CT scan) or pulmonary function tests, to assess your lung function and rule out any serious conditions. Additionally, monitoring your blood pressure and heart rate during these episodes can provide valuable information.

In summary, while shortness of breath can be alarming, understanding the potential causes can help guide appropriate management. It is crucial to communicate openly with your healthcare team about your symptoms, especially since they have occurred multiple times in a short period. They can help you navigate this complex situation and ensure that any underlying issues are addressed effectively.

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