Is My Hand Tremor a Sign of Early Parkinson's Disease? - Neurology

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Could this be a sign of Parkinson's disease?


Hello Doctor: I am 29 years old and about two years ago, I noticed that my right index finger would occasionally tremble slightly.
This usually occurs after actions that engage the muscles of the index finger, such as opening bottle caps, brushing my teeth, or writing.
The trembling stops after a while, but sometimes it happens even when I am at rest.
During the tremor, I can see the muscle between my index finger and thumb contracting, pulling the index finger towards the thumb.
The frequency of the tremors varies; sometimes it occurs once per second with a longer movement, and other times several times per second with shorter movements, but the distance never exceeds one centimeter.
In terms of frequency, it happens several times a day, and I can also intentionally trigger it by clenching my fist or opening a bottle cap.

Later, this symptom ceased, and after a while, my thumb began to tremble, moving towards the index finger.
Eventually, the thumb tremors stopped, and then the middle finger started to exhibit the same symptoms (also moving towards the index finger), with visible muscle contractions between the index and middle fingers.
Recently, the middle finger has been the one trembling.
Additionally, my left thumb has also trembled occasionally, but very infrequently—perhaps once a week, with only one or two jumps each time.

In summary, over the past two years, it started with my right index finger, then my right thumb, and now my right middle finger.
The left hand occasionally shows symptoms, but very rarely.
It feels like the muscles are twitching on their own, and sometimes tremors occur even when both hands are at rest.
I researched Parkinson's disease symptoms online and found that early symptoms include hand tremors and rubbing movements between the index and thumb, but I do not currently experience these.
However, I do match the description of how tremors in Parkinson's disease often start in the thumb, index, and middle fingers of one hand.
Furthermore, I read that later-stage Parkinson's patients may experience tremors in facial muscles such as the lips, tongue, and chin.
Occasionally, I also notice twitching in these areas, which began about two years ago, aligning somewhat with the symptoms.
Two years ago, I visited a doctor at Mackay Memorial Hospital in Hsinchu, who mentioned that I might have essential tremor.
Regarding the symptoms, the doctor said that as long as there is no significant shaking, it should be fine.
At that time, I had no issues touching my nose and the doctor's finger with my index finger.
Additionally, I have been experiencing unexplained dizziness for the past four years, and despite undergoing examinations in neurology departments at major hospitals and having an electromyogram, no cause has been identified.
Besides my fingers, I sometimes experience muscle twitching in different areas of my arms, with the locations being inconsistent.
Doctor, do my symptoms resemble the early signs of Parkinson's disease? Although I know the likelihood of early-onset Parkinson's is low, I am quite concerned as I may be getting married within a year.
I hope you can help clarify my worries.
Thank you, Doctor; I greatly appreciate it.

Xiao Hao, 20~29 year old female. Ask Date: 2010/03/15

Dr. Zeng Kongyan reply Neurology


Hello: In response to your question, based on the description provided in your letter, it does not appear to be Parkinson's disease, as the tremors associated with this condition typically occur at rest and have a frequency of 4-8 Hz.
If Dr.
Mackay diagnosed it as essential tremor, then it occurs during movement and has a faster frequency of 8-12 Hz.
Regarding the different muscle twitches, it is advisable to continue monitoring.
If the symptoms worsen, an electromyography (EMG) test should be conducted at the same hospital to determine the underlying cause.

Reply Date: 2010/03/15

More Info


Your concerns about the tremors in your hand and the possibility of early Parkinson's disease are understandable, especially given the complexity of the symptoms you’re experiencing. Let's break down your symptoms and the potential implications.

Firstly, it's important to note that tremors can arise from a variety of causes, and not all tremors are indicative of Parkinson's disease. The tremors you describe, which occur primarily in your right hand's fingers during specific activities (like opening a bottle or brushing your teeth), could be related to essential tremor, a common movement disorder that is often benign and not associated with Parkinson's disease. Essential tremor typically manifests as a postural or action tremor, meaning it occurs when you are using the muscles, rather than at rest, which is more characteristic of Parkinson's disease.

In Parkinson's disease, the tremors often start in one hand and are typically more pronounced at rest. They can also be accompanied by other symptoms such as rigidity, bradykinesia (slowness of movement), and postural instability. You mentioned that your tremors stop during activities and that you do not experience significant tremors at rest, which is not typical for Parkinson's disease. Additionally, the fact that your symptoms have shifted from one finger to another over time suggests a pattern that may not align with Parkinson's.

The muscle twitching you experience in other parts of your body, including your arms and facial muscles, could be related to benign fasciculation syndrome or other non-serious neurological conditions. These muscle twitches are often benign and can be exacerbated by stress, fatigue, or caffeine intake.

Your previous consultation with a neurologist, who suggested that you might have essential tremor, aligns with the information you provided. It’s also worth noting that the absence of significant motor impairment during your examination (such as the ability to touch your nose and the doctor’s finger without issue) is a positive sign.

Given your age (29 years old), the likelihood of developing early-onset Parkinson's disease is low, although it is not impossible. Early-onset Parkinson's typically presents with more pronounced symptoms and a more rapid progression than what you have described.
If you are experiencing anxiety about your symptoms, it may be beneficial to discuss this with a healthcare professional. Anxiety can exacerbate physical symptoms and create a cycle of worry that may make your symptoms feel worse. Cognitive-behavioral therapy (CBT) or mindfulness practices can be effective in managing health-related anxiety.

In conclusion, while your symptoms warrant monitoring, they do not strongly indicate early Parkinson's disease based on the information provided. It would be advisable to continue regular follow-ups with your neurologist, who can provide ongoing assessment and reassurance. If your symptoms change or worsen, or if you develop new symptoms, make sure to seek medical advice promptly. Remember, maintaining a healthy lifestyle, including regular exercise and stress management, can also contribute positively to your overall well-being.

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