Salivary Gland Tumors and Nasopharyngeal Cancer Risks

Q: Salivary Gland Tumors and Nasopharyngeal Cancer Risks

Dear Inquirer： Hello, regarding your EB test, you may follow the recommendations of your attending physician. <br>As for your father, it is advised to have at least one examination of the nasopharynx; the physician can use either a mirror or an endoscope for this. <br>Sincerely,

Salivary gland (parotid gland) tumors and nasopharyngeal carcinoma?

Hello Dr.
Chen, thank you for your sincere response to my previous question regarding the EB virus.
Today, I went for a follow-up appointment with the otolaryngology department.
Last year, my EB test result was in the yellow zone.
Later, in January of this year, I underwent a nasopharyngoscopy and EB testing at Mackay Memorial Hospital.
The results showed that my nasopharynx was normal, but the EB test did not show yellow (IgA), although there was another analysis that was indeterminate (with a value of over 2, and the doctor mentioned that positive is 6).
During today's follow-up, the nasopharyngoscopy was normal, and the doctor advised me to extend the follow-up period to six months.

I also inquired about my father during my last visit.
He has a tumor located below his ear, and today we reviewed the tumor report.
The doctor stated that it is a benign salivary gland tumor.
I suspect it might be a parotid gland tumor since it is located below the ear.
From my research online, I found that most parotid gland tumors are benign.
I am relieved that my father's tumor is benign.
However, I still advised him to visit the otolaryngology department again, as his initial consultation, which included tumor removal, was conducted in the plastic surgery department.
After reviewing the above cases, I wonder if Dr.
Chen has any suggestions.
Thank you very much for your response.

Mr. Huang, 20~29 year old female. Ask Date: 2010/04/08

Dr. Chen Jianzhi reply Otolaryngology

Dear Inquirer: Hello, regarding your EB test, you may follow the recommendations of your attending physician.
As for your father, it is advised to have at least one examination of the nasopharynx; the physician can use either a mirror or an endoscope for this.
Sincerely, Dr.
Chen Jian-Zhi, Lecturer at Fu Jen Catholic University and Physician at Taoyuan Hospital, Department of Health.

Reply Date: 2010/04/08

More Info

Understanding salivary gland tumors and their association with nasopharyngeal cancer risks is crucial for both patients and healthcare providers. Salivary gland tumors can be benign or malignant, with the parotid gland being the most common site for these tumors. Benign tumors, such as pleomorphic adenomas (also known as "benign mixed tumors"), are indeed more prevalent, particularly in the parotid gland. However, malignant tumors, including mucoepidermoid carcinoma and adenoid cystic carcinoma, can also arise in these glands and may require more aggressive treatment.

Your father's diagnosis of a benign salivary gland tumor is reassuring, as the majority of salivary gland tumors are benign. The most common benign tumor, the pleomorphic adenoma, typically presents as a painless swelling in the region of the gland, which aligns with your father's case. Surgical excision is often the treatment of choice, and the prognosis for benign tumors is generally excellent, with a low recurrence rate if completely excised.

Regarding your concerns about nasopharyngeal cancer, it is important to note that there is a well-established association between Epstein-Barr Virus (EBV) and nasopharyngeal carcinoma (NPC). EBV is a common virus that can remain dormant in the body after initial infection, and in some individuals, it can contribute to the development of NPC. The presence of IgA antibodies against viral capsid antigen (VCA) can indicate a past infection, but the significance of the "yellow light" or borderline results can vary. Your recent normal nasopharyngeal endoscopy is a positive sign, and the decision to extend follow-up to six months is a common practice to monitor for any changes.

It is also worth noting that while EBV is a risk factor for NPC, not everyone with EBV will develop this cancer. Other factors, including genetic predisposition, environmental influences, and lifestyle choices, also play a role in the development of NPC. Regular follow-up and monitoring are essential, especially if there are any risk factors present.

In summary, your father's benign salivary gland tumor is a positive outcome, and continued follow-up with an ear, nose, and throat (ENT) specialist is advisable to ensure proper management. For your own health, maintaining regular check-ups and monitoring for any symptoms is crucial, especially given the association between EBV and nasopharyngeal cancer. If you have any further concerns or symptoms, do not hesitate to discuss them with your healthcare provider. Early detection and intervention are key in managing any potential health issues.

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