Multiple Sclerosis
Hello, my sister's multiple sclerosis has relapsed again, and I am very worried.
I would like to ask you about something.
Everyone online says that for acute episodes, high-dose steroids should be injected, so we went to the emergency room.
After the injection, she felt immediate relief, but by the evening, without further injections, she experienced severe pain in her head and back, making it impossible to sleep all night! After receiving another dose (the doctor said the evening dose should be lower), it quickly lost its effectiveness.
It seems the doctor is hesitant to administer high doses continuously.
Is it possible to keep her on intravenous steroids for two to three days to suppress the relapse? Does there have to be such a long interval? Today is the second day; she received steroids in the morning, but the effect is not as good as the first day.
She is still experiencing severe pain in her head and body, feels weakness in her legs, and has urinary incontinence! I'm really anxious.
Thank you! Sue
Sue, 30~39 year old female. Ask Date: 2010/04/20
Dr. Huang Yongquan reply Neurology
Hello: In response to your question, if a diagnosis of multiple sclerosis is confirmed, the standard treatment involves administering high-dose corticosteroids in the morning and evening, or using plasmapheresis to adjust the immune system.
During the acute phase, continuous treatment is required for 7-10 days.
As you mentioned experiencing neurological symptoms, it is important to seek medical attention and consider hospitalization for treatment as soon as possible.
Reply Date: 2010/04/20
More Info
Managing multiple sclerosis (MS) relapses can be a challenging experience for both patients and their families. Your concern for your sister is completely understandable, especially when dealing with the acute symptoms that can arise during a relapse. Let’s delve into the treatment options, particularly the use of steroids, and address your questions regarding their administration.
Multiple sclerosis is an autoimmune disease that affects the central nervous system, leading to a variety of symptoms, including fatigue, weakness, pain, and cognitive issues. During a relapse, these symptoms can worsen significantly, and the goal of treatment is to reduce inflammation and speed up recovery. High-dose corticosteroids, such as methylprednisolone, are commonly used to manage acute relapses. They work by suppressing the immune response and reducing inflammation in the nervous system.
In your sister's case, it sounds like she received a high-dose steroid injection, which is a standard approach for managing acute MS relapses. The immediate relief she experienced is not uncommon, as steroids can quickly reduce inflammation and alleviate symptoms. However, the subsequent pain and discomfort she experienced after the initial treatment can be attributed to several factors, including the nature of MS itself and the body's response to steroid treatment.
Regarding your question about the continuous administration of steroids, it is important to note that while high-dose steroids can be effective in the short term, they are not without risks. Prolonged use of high-dose steroids can lead to significant side effects, including increased blood sugar levels, mood changes, and potential damage to other organs. Therefore, healthcare providers typically limit the duration and dosage of steroid treatments to minimize these risks.
The standard protocol for steroid treatment during an MS relapse is usually a course of intravenous (IV) steroids for three to five days, followed by a tapering dose of oral steroids if necessary. This approach helps to manage the relapse while also reducing the risk of side effects associated with prolonged high-dose steroid use.
If your sister is experiencing severe pain and other symptoms like urinary incontinence, it is crucial to communicate these issues with her healthcare provider. They may consider adjusting her treatment plan, which could include pain management strategies, physical therapy, or other medications that can help alleviate her symptoms.
In terms of managing her pain and discomfort, there are several supportive measures that can be beneficial. These include:
1. Pain Management: Over-the-counter pain relievers or prescribed medications can help manage pain. It's important to consult her doctor before taking any new medications.
2. Physical Therapy: Engaging in physical therapy can help improve mobility and reduce pain through targeted exercises and stretches.
3. Hydration and Nutrition: Staying well-hydrated and maintaining a balanced diet can support overall health and recovery.
4. Rest and Relaxation: Ensuring she gets adequate rest and engages in relaxation techniques can help manage stress and improve her overall well-being.
5. Monitoring Symptoms: Keeping a detailed record of her symptoms, including when they worsen or improve, can provide valuable information for her healthcare team.
In conclusion, while high-dose steroids are a common and effective treatment for acute MS relapses, they must be used judiciously to avoid potential side effects. Continuous administration of steroids is generally not recommended without careful consideration and monitoring by a healthcare professional. It is essential to maintain open communication with her healthcare team to ensure that her treatment plan is tailored to her specific needs and that any side effects or new symptoms are addressed promptly. Your support and advocacy for her health are invaluable during this challenging time.
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