Gastroesophageal reflux disease (GERD)
Hello Doctor: I have been experiencing gastroesophageal reflux for almost 4 months now.
I have undergone various tests including gastroscopy, X-rays, blood tests, and ultrasound.
The gastroscopy report indicated that there is erosion in my stomach, while the other X-ray-related tests were normal.
I mentioned to my doctor that I was experiencing stomach discomfort and occasional acid reflux into my esophagus, but it was infrequent, about 1 to 2 times a week.
Currently, I am taking Nexium (PPI), Gascon (for gas relief), and Domperidone (to accelerate gastric emptying).
In the first 3 months, I did not take the medication consistently because I would stop when my symptoms improved, and I also made the mistake of lying down after eating lunch.
As a result, when the medication wore off, I started experiencing discomfort again.
I returned for a follow-up appointment in early April, and my doctor was surprised that my condition had not improved.
I was prescribed another 2 weeks of Nexium (due to the health insurance policy, I can only get a 2-week supply of PPI).
I also scheduled a follow-up appointment for next month.
Additionally, I have corrected my habit of lying down after lunch and have been taking my medication consistently.
Currently, even though I am taking Nexium, I still experience stomach discomfort around noon.
Yesterday, I took a Gelusil tablet and felt much better.
It seems that excess stomach acid is causing my discomfort.
I would like to ask you: 1.
Isn’t Nexium supposed to effectively suppress stomach acid? Why am I still experiencing excess stomach acid? Should I consider changing my medication? 2.
Can I take Gelusil with my three meals? 3.
Given my situation, do I need to undergo another gastroscopy? Thank you.
Michael, 40~49 year old female. Ask Date: 2010/04/27
Dr. Chen Qifeng reply Gastroenterology and Hepatology
Hello,
1.
Nexium is currently one of the most potent acid-suppressing medications available, but individual "dosage requirements" may vary.
Some GERD patients may need to take it twice a day to adequately relieve their symptoms (however, health insurance does not cover two tablets a day).
2.
It is feasible to use Gelusil as needed in conjunction with Prw.
3.
After four months of treatment, it may be considered to perform an endoscopy for evaluation.
Additionally, for gastric cancer with ulceration, it is important to check for the presence of Helicobacter pylori.
Wishing you good health,
Dr.
Chi-Feng Chen, Taoyuan Hospital, Department of Health
Reply Date: 2010/04/27
More Info
Managing gastroesophageal reflux disease (GERD) can be quite challenging, especially when symptoms persist despite treatment. Your situation, characterized by ongoing discomfort and the need for medication adjustments, is not uncommon among individuals dealing with GERD. Let’s address your questions and provide some insights into your condition.
1. Nexium and Acid Control: Nexium (esomeprazole) is a proton pump inhibitor (PPI) that effectively reduces stomach acid production. However, some patients may still experience symptoms of acid reflux despite being on PPIs. This can occur for several reasons:
- Incomplete Acid Suppression: While PPIs are effective, they may not completely eliminate acid production in all individuals. Some patients may require higher doses or a different PPI for better control.
- Rebound Acid Hypersecretion: After stopping PPIs, some individuals may experience increased acid production, leading to a rebound effect. This could explain why symptoms return when medication is not taken consistently.
- Other Factors: Lifestyle factors, such as diet, eating habits, and body position after meals, can also contribute to reflux symptoms. For instance, lying down after eating can exacerbate GERD symptoms, as gravity helps keep stomach contents in the stomach.
2. Using Gelusil with Meals: Gelusil is an antacid that can help neutralize stomach acid and provide quick relief from discomfort. It is generally safe to use Gelusil in conjunction with your meals, especially if you find it alleviates your symptoms. However, it’s important to space out the timing of antacids and PPIs. Taking antacids too close to your PPI dose may interfere with the absorption of the PPI, reducing its effectiveness. A good rule of thumb is to take antacids at least 2 hours apart from your PPI.
3. Need for Repeat Endoscopy: Whether you need another endoscopy depends on your symptoms and the findings from your previous examinations. If your symptoms are not improving with medication and lifestyle changes, or if you experience new or worsening symptoms (such as difficulty swallowing, significant weight loss, or persistent vomiting), it may be prudent to discuss the need for repeat endoscopy with your doctor. This can help assess the state of your esophagus and stomach lining, check for any complications, and ensure that there are no new issues that require attention.
In addition to addressing your specific questions, it’s essential to consider some general management strategies for GERD:
- Dietary Modifications: Avoid foods and beverages that trigger your symptoms, such as spicy foods, citrus, chocolate, caffeine, and fatty foods. Eating smaller, more frequent meals can also help.
- Lifestyle Changes: Maintain a healthy weight, avoid lying down after meals, and elevate the head of your bed to reduce nighttime symptoms.
- Medication Adherence: Consistently taking your medications as prescribed is crucial for managing GERD. If you notice that your symptoms are not well-controlled, discuss this with your healthcare provider, as they may need to adjust your treatment plan.
In conclusion, managing GERD often requires a multifaceted approach that includes medication, lifestyle changes, and dietary modifications. If your symptoms persist or worsen, it’s important to maintain open communication with your healthcare provider to explore further diagnostic options and treatment adjustments. Your proactive approach to managing your condition is commendable, and with the right strategies, you can work towards better symptom control and improved quality of life.
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