Testicular Lumps: Is It Cancer or Just a Cyst? - Urology

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Testicular issues?


Hello, doctor.
I found a small hard lump on my right testicle.
Since it is not painful or itchy, and I have had regular liver checks with normal alpha-fetoprotein levels, I haven't rushed to see a doctor.
However, a few months have passed, and the lump is still there.
Can the normal alpha-fetoprotein levels rule out the possibility of testicular cancer, and could it just be something like a cyst?

yuyu, 30~39 year old female. Ask Date: 2010/05/03

Dr. Xu Wencang reply Urology


Hello: In response to your question, a scrotal ultrasound (testicular and epididymal) can be performed to differentiate the characteristics and location of the masses.
Normal fetal protein levels do not rule out the possibility of testicular cancer.

Reply Date: 2010/05/03

More Info


When it comes to testicular lumps, distinguishing between benign conditions, such as cysts, and malignant ones, like testicular cancer, can be challenging. The presence of a hard lump in the testicle can understandably cause concern, especially if it persists over time. In your case, the fact that the lump is small, hard, and asymptomatic (not painful or itchy) is somewhat reassuring, but it does not completely rule out the possibility of testicular cancer.

Firstly, it is important to understand that testicular cancer can present in various ways. While some tumors may be painful, many are not, and they can be detected as hard lumps or masses in the testicle. The texture of the lump can vary, and it may feel irregular or smooth. The presence of a lump does not automatically indicate cancer, but it is a sign that warrants further investigation.

Regarding your question about the normal levels of alpha-fetoprotein (AFP), this is a crucial point. AFP is a tumor marker that can be elevated in certain types of testicular cancer, particularly non-seminomatous germ cell tumors. However, it is important to note that not all testicular cancers will result in elevated AFP levels. Some seminomas, for instance, may not produce this marker. Therefore, while normal AFP levels can reduce the likelihood of certain types of testicular cancer, they do not completely exclude the possibility of malignancy.

In addition to AFP, other tumor markers such as human chorionic gonadotropin (hCG) and lactate dehydrogenase (LDH) may also be evaluated. A comprehensive assessment of these markers, along with imaging studies, can provide a clearer picture of the situation.

Given that the lump has persisted for several months, it is advisable to seek further evaluation from a healthcare professional, preferably a urologist. They may recommend a scrotal ultrasound, which is a non-invasive imaging technique that can help differentiate between solid masses and cystic structures. An ultrasound can provide valuable information about the characteristics of the lump, such as its size, shape, and whether it has blood flow, which can indicate malignancy.

In summary, while normal AFP levels are a positive sign, they do not definitively rule out testicular cancer. The persistence of the lump, despite being asymptomatic, is a reason to pursue further evaluation. Early detection and diagnosis are crucial in managing testicular cancer effectively, should it be present. Therefore, I encourage you to consult with a urologist for a thorough examination and appropriate imaging studies to ensure peace of mind and proper management of your condition.

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