Does Creatine in Protein Powder Cause Skin Itching? - Family Medicine

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Does creatine cause itching of the skin?


Hello, Doctor.
I usually engage in weight training and take nutritional supplements.
The whey protein I typically consume does not contain creatine.
Last week, I bought a whey protein that contains creatine (which I take before training).
Strangely, in the past few days after consuming it, I've experienced intense itching on my skin, especially on my upper limbs, scalp, and around my navel.
There are no visible rashes or lesions, just severe itching...
to the point of being unbearable.
Therefore, I stopped drinking that creatine-containing whey protein yesterday, and the itching subsided.
The ingredients in that whey protein include maltodextrin, corn syrup, fructose, alpha-amylase, lipase, lecithin, creatine, guar gum, flavoring, cocoa, glucose, pineapple enzyme, papaya enzyme, guarana extract, whey protein concentrate, casein calcium, egg white, ion-exchanged whey protein, sweet whey powder, magnesium oxide, choline bitartrate, calcium carbonate, inositol, vitamin C, biotin, ferrous fumarate, vitamin E, vitamin A, niacinamide, copper gluconate, potassium iodide, zinc oxide, calcium pantothenate, folic acid, vitamin D3, vitamin B2, vitamin B6, vitamin B1, and vitamin B12.
What could be causing my skin to itch so much? To be honest, I'm not sure which specialty to consult regarding this issue, so I wanted to discuss it with you first.
Thank you, Doctor.

Jiaoliang, 20~29 year old female. Ask Date: 2010/05/09

Dr. Chen Mengkan reply Family Medicine


Hello: Regarding your symptoms, it seems that you may be experiencing an allergic reaction to a component in the whey protein you consumed, or it could be triggered by exposure to other environmental factors.
Substances containing protein components are more likely to cause allergic reactions.
For example, the ingredients you listed, such as creatine, bromelain, papain, guarana extract, whey protein concentrate, casein calcium, egg albumin, ion-exchanged whey protein, and sweet whey powder, could all potentially be responsible.
It is advisable to stick with the ingredients you typically use.
Thank you!

Reply Date: 2010/05/09

More Info


It seems that you are experiencing significant skin itching after consuming a protein powder that contains creatine, which is a common supplement among those engaged in weight training. Your symptoms, particularly the itching localized to your upper limbs, scalp, and sides of your abdomen, could indeed be linked to the ingredients in the protein powder, including creatine.
Firstly, it's important to note that while creatine itself is not typically associated with skin reactions, the itching you are experiencing may be due to an allergic reaction or sensitivity to one of the other ingredients in the protein powder. The list of ingredients you provided includes various proteins, enzymes, and additives, any of which could potentially trigger an allergic response. For instance, whey protein, which is derived from milk, can cause reactions in individuals who are lactose intolerant or allergic to dairy. Similarly, other components like egg protein or even flavoring agents could be culprits.

In your case, since you mentioned that the itching subsided after you stopped consuming the creatine-containing protein powder, it strongly suggests that one or more ingredients in that specific formulation are responsible for your symptoms. The itching could be a manifestation of a histamine response, which is common in allergic reactions.
Additionally, the environment can also play a role in skin reactions. You mentioned that the air quality has been poor, which could exacerbate skin sensitivity or irritation. Pollutants and allergens in the air can lead to skin issues, especially if your skin is already compromised or sensitive due to dietary changes.

To address your concerns, here are some recommendations:
1. Discontinue Use: As you've already done, it's wise to stop using the protein powder that caused the reaction.
2. Consult a Dermatologist: If the itching persists or worsens, it would be beneficial to consult a dermatologist. They can perform tests to determine if you have an allergy to any of the ingredients in the protein powder.

3. Patch Testing: A dermatologist may recommend patch testing to identify specific allergens. This can help pinpoint which ingredient is causing your reaction.

4. Consider Alternatives: If you are looking for protein supplements, consider options that are free from common allergens. Plant-based protein powders, for example, may be a suitable alternative if you suspect dairy or egg proteins are the issue.

5. Monitor Your Skin: Keep an eye on your skin's response to other products and dietary changes. If you introduce new supplements or skincare products, do so one at a time to identify any potential triggers.

6. Hydration and Skin Care: Ensure you are keeping your skin well-hydrated. Sometimes, dryness can exacerbate itching. Use gentle, fragrance-free moisturizers to help soothe your skin.

In conclusion, while creatine itself is unlikely to be the direct cause of your itching, the protein powder's formulation could contain allergens or irritants that are affecting your skin. By discontinuing its use and consulting with a healthcare professional, you can better understand your symptoms and find a suitable solution.

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