Your Dermatology Medications: A Guide to Usage and Effects - Pharmacology

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Inquiry about dermatological medications?


Hello, Pharmacist: A few days ago, I visited a dermatologist who prescribed me the following topical ointments/gels.
The details of the medications are as follows: 1.
DALCINE GEL, apply three times a day for three days; 2.
HEPARINOID OINTMENT, as needed for three days to reduce swelling; 3.
DERMA-E CREAM, apply at bedtime for three days; 4.
TRETINOIN GEL, apply at bedtime for three days; 5.
KETONA SHAMPOO, use once a day for three days.
She gave me four small round jars but did not specify the items.
They are divided for acne treatment, acne scar treatment, blackheads on the nose, and other areas.
The details indicate that items 3 and 4 are to be used at bedtime, and the jars labeled for bedtime use are for blackheads on the nose and other areas.
Item 5 is a facial wash, which is a translucent gel with a peach-pink color.
The medication for the blackheads on the nose has a somewhat pungent smell, and there is a slight stinging sensation upon application.
I am unsure if this is due to the individual medication or an interaction with other medications, as my nose has started to peel! I hope for a detailed explanation.
Thank you :)

BOW, 20~29 year old female. Ask Date: 2010/06/01

Dr. Liao Huiling reply Pharmacology


Hello! Regarding the therapeutic uses of individual medications for your skin symptoms, it is advisable to consult your physician during your visit to avoid any misunderstandings that may arise from explanations given by others afterward.
Topical medications for treating acne and comedones may cause side effects such as photosensitivity or peeling, which typically resolve after discontinuation of the medication, so there is no need for excessive worry.
Wishing you health and happiness!

Reply Date: 2010/06/01

More Info


Understanding your dermatology medications is crucial for effective treatment and managing any potential side effects. Let's break down the medications you've been prescribed, their uses, and any relevant side effects or interactions.


1. DALCINE GEL (Clindamycin Phosphate Gel)
Usage: This topical antibiotic is typically applied three times a day to treat acne. Clindamycin works by inhibiting bacterial protein synthesis, which helps reduce the number of acne-causing bacteria on the skin.

Effects: It can help reduce inflammation and prevent new acne lesions from forming.
Side Effects: Common side effects may include dryness, irritation, or peeling of the skin. If you experience severe irritation or an allergic reaction, you should contact your healthcare provider.


2. HEPARINOID OINTMENT
Usage: This ointment is often used to reduce swelling and promote healing. It can be applied as needed, typically three times a day, to areas that require decongestion or healing.

Effects: Heparinoid has anti-inflammatory properties and can help with bruising or swelling.

Side Effects: While generally well-tolerated, some individuals may experience skin irritation or allergic reactions.

3. DERMA-E CREAM
Usage: This cream is usually applied at bedtime. Depending on its formulation, it may contain ingredients like vitamins or antioxidants that help nourish and repair the skin.

Effects: It can help hydrate the skin and may improve the appearance of scars or uneven skin tone.

Side Effects: Possible side effects include mild irritation or allergic reactions, particularly if you have sensitive skin.


4. TRETINOIN GEL
Usage: Tretinoin is a topical retinoid applied at night. It is effective for treating acne and improving skin texture and tone.

Effects: It promotes cell turnover, helping to prevent clogged pores and reduce the appearance of fine lines and hyperpigmentation.

Side Effects: Common side effects include redness, peeling, dryness, and increased sensitivity to sunlight. It is crucial to use sunscreen during the day while using this medication.


5. KETONA SHAMPOO (Ketoconazole Shampoo)
Usage: This medicated shampoo is typically used once daily to treat dandruff or seborrheic dermatitis.
Effects: Ketoconazole is an antifungal that helps reduce flaking and itching associated with fungal infections of the scalp.

Side Effects: Some users may experience scalp irritation or an oily scalp. If you notice any severe reactions, consult your healthcare provider.


Interaction and Combined Use
You mentioned experiencing a stinging sensation and peeling skin, particularly with the nasal application. This could be due to the combined effects of the medications, especially with Tretinoin, which is known to cause skin irritation, particularly when first introduced.

Recommendations
1. Monitor Skin Reactions: Keep an eye on how your skin responds to these medications. If irritation persists or worsens, consult your dermatologist.

2. Sun Protection: Since Tretinoin increases sun sensitivity, ensure you apply sunscreen during the day.

3. Application Order: Generally, apply lighter formulations first (like gels) and thicker creams last. If you're unsure about the order, ask your pharmacist or dermatologist.

4. Hydration: Consider using a gentle moisturizer to help combat dryness from Tretinoin and Clindamycin.

In conclusion, understanding your medications and their effects is vital for maximizing their benefits while minimizing side effects. Always communicate with your healthcare provider about any concerns or unusual reactions you experience during your treatment.

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