Can Faba Bean Patients Use Acne Cream? Expert Advice on Safety - Dermatology

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Hello, can patients with Favism use the Apricot Blossom Acne Lotion (Taiwan FDA Drug Code 033153)? When I visited Chang Gung Hospital, the doctor prescribed this ointment for me to apply, but I later noticed that the label on the bottle states that it should not be used by patients with Favism.
However, I have been using it for several days without any discomfort.
Is it still appropriate for me to continue using it?

Lai, 10~19 year old female. Ask Date: 2010/06/27

Dr. Huang Ruiyun reply Dermatology


Hello: Its ingredient is precipitated sulfur, which is for external use only and is not included in the list of contraindications for patients with favism.
It is possible that the labeler confused it with other sulfur-containing compounds; some labels from Hsin Kuei Pharmaceutical Company seem to be a bit excessive.
Wishing you safety.

Reply Date: 2010/06/27

More Info


When it comes to the use of acne creams or any topical products by patients with G6PD deficiency (also known as faba bean disease), caution is paramount. G6PD deficiency is a genetic condition that affects the enzyme responsible for protecting red blood cells from damage. Certain substances can trigger hemolytic anemia in these patients, leading to serious health complications.

In your case, you mentioned using an acne cream called "杏輝蜜花面皰擦液" (which translates to "Hsin Wei Honey Flower Acne Liquid"). It's important to note that while you have not experienced any adverse effects after using the product for several days, the label warning against use by G6PD deficiency patients should not be taken lightly. The fact that the product has a warning indicates that it may contain ingredients that could potentially trigger a reaction, even if you have not yet experienced any symptoms.

The key ingredients in many acne treatments can include salicylic acid, benzoyl peroxide, and various plant extracts. While some of these ingredients are generally considered safe for G6PD deficiency patients, others may not be. For instance, certain essential oils, menthol, and camphor are known to pose risks for individuals with this condition. If the acne cream contains any of these ingredients, it could potentially lead to hemolysis, even if you have not experienced any immediate side effects.

Given the complexity of G6PD deficiency and the variability in individual reactions to different substances, it is crucial to consult with a healthcare professional who is knowledgeable about this condition before continuing to use the acne cream. They can provide personalized advice based on your medical history and the specific ingredients in the product.

In addition, if you are experiencing acne, there are alternative treatments that may be safer for individuals with G6PD deficiency. These can include topical treatments that do not contain potentially harmful ingredients, such as certain types of non-comedogenic moisturizers or gentle cleansers. Always look for products that are specifically labeled as safe for sensitive skin or for individuals with specific health conditions.

In summary, while you may not have experienced any adverse effects from using the acne cream, the warning on the label should not be ignored. It is advisable to stop using the product and consult with a healthcare professional for safer alternatives. Your health and safety should always come first, especially when dealing with a condition like G6PD deficiency.

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