Possible Causes of Mouth Sores on Both Sides: Expert Insights - Dentistry

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Ulceration on both sides of the oral cavity?


Hello Dr.
Tseng, I have recently been experiencing sores on both sides of my mouth that are not caused by any external injury.
Could you please advise what might be the cause? Thank you.

A-Ming, 20~29 year old female. Ask Date: 2010/07/25

Dr. Zeng Guanghui reply Dentistry


Hello, sir: Thank you for your inquiry.
I would like to respond to your question and provide the following advice: Persistent sores in the oral cavity may be indicative of recurrent aphthous ulcers.
Generally, if there is significant mental stress, emotional tension, or lack of sleep leading to immune system dysregulation, symptoms of ulceration may frequently occur.
Additionally, it is important to consider whether sharp teeth or ill-fitting dentures may be contributing to the oral ulcerations.
I recommend consulting a dentist for diagnosis and treatment.
Wishing you peace and happiness!

Reply Date: 2010/07/25

More Info


Mouth sores can be a frustrating and painful condition, and their appearance on both sides of the mouth can be particularly concerning. There are several potential causes for these sores, and understanding them can help in managing the symptoms and seeking appropriate treatment.

1. Aphthous Stomatitis: One of the most common causes of mouth sores is aphthous stomatitis, also known as canker sores. These are small, painful ulcers that can appear on the soft tissues of the mouth, including the inside of the cheeks, gums, and tongue. The exact cause of canker sores is not well understood, but they are often triggered by stress, hormonal changes, certain foods (like citrus or spicy foods), and nutritional deficiencies (especially vitamin B12, folate, and iron).

2. Oral Lichen Planus: This is a chronic inflammatory condition that can cause white patches, redness, and sores in the mouth. It is thought to be an autoimmune disorder, where the immune system mistakenly attacks the cells in the oral mucosa. Patients may experience pain and discomfort, particularly when eating or drinking.

3. Herpes Simplex Virus: The herpes simplex virus can cause recurrent sores in the mouth, commonly referred to as cold sores or fever blisters. While these typically appear on the lips, they can also manifest inside the mouth. The sores can be painful and are often accompanied by other symptoms such as fever or swollen lymph nodes.

4. Allergic Reactions: Allergies to certain foods, dental products, or medications can lead to the development of mouth sores. If you have recently changed any products or introduced new foods into your diet, this could be a potential cause.

5. Nutritional Deficiencies: Deficiencies in essential vitamins and minerals can lead to the development of mouth sores. For example, a lack of vitamin C (scurvy) or vitamin B12 can result in sores and other oral health issues. Ensuring a balanced diet rich in fruits, vegetables, and whole grains can help prevent these deficiencies.

6. Irritation or Trauma: While you mentioned that the sores are not caused by external trauma, it’s worth noting that irritation from dental appliances (like braces or dentures), rough teeth, or even aggressive brushing can lead to sores.
7. Systemic Conditions: Certain systemic conditions, such as inflammatory bowel disease (IBD), Behçet's disease, or even some types of cancer, can manifest with oral symptoms, including sores. If the sores persist or are accompanied by other systemic symptoms (like weight loss, fever, or gastrointestinal issues), it is crucial to seek medical evaluation.

8. Stress and Hormonal Changes: Psychological stress and hormonal fluctuations can also contribute to the development of mouth sores. Stress can weaken the immune system, making one more susceptible to infections and ulcers.

Given the variety of potential causes, it is essential to monitor the sores closely. If they persist for more than a week, worsen, or are accompanied by other concerning symptoms (such as fever, difficulty swallowing, or significant pain), it is advisable to consult a healthcare professional. A dentist or an oral specialist can provide a thorough examination and may recommend treatments such as topical medications, mouth rinses, or dietary adjustments based on the underlying cause.

In the meantime, maintaining good oral hygiene, avoiding irritants (like spicy or acidic foods), and managing stress can help alleviate symptoms. Additionally, staying hydrated and using a soft-bristled toothbrush can minimize irritation in the mouth. If nutritional deficiencies are suspected, consider discussing dietary changes or supplements with a healthcare provider.

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