Provera 5mg: Menstrual Cycle and Side Effects Explained - Obstetrics and Gynecology

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Questions regarding Provera 5mg?


My girlfriend is 20 years old.
She was originally taking progesterone to regulate her menstrual cycle, but this month she either took the wrong medication or something else happened.
After her period ended, she took 5 mg of Provera every day for 21 consecutive days.
How long after finishing the medication will her period come? Are there any adverse side effects? What would be a better approach for regulating her menstrual cycle next time? Thank you.

Xiao Chen, 30~39 year old female. Ask Date: 2010/08/07

Dr. Chen Changfu reply Obstetrics and Gynecology


Provera is a derivative of progesterone used for the treatment of abnormal uterine bleeding (AUB) without organic disease, commonly referred to as menstrual regulation.
It is typically administered during the last 1 to 2 weeks of the menstrual cycle.
Please follow the prescribing obstetrician-gynecologist's instructions and do not self-medicate.
After discontinuation of the medication, most patients will experience withdrawal bleeding within 1 to 2 weeks.
Side effects of the medication can be found online and may include breast tenderness, galactorrhea, irregular vaginal bleeding, and changes in the menstrual cycle, among others.
If you experience irregular vaginal bleeding (commonly referred to as dysfunctional uterine bleeding), it is essential to consult an obstetrician-gynecologist for proper evaluation and treatment following a gynecological examination.

Reply Date: 2010/08/07

More Info


Provera (medroxyprogesterone acetate) is a synthetic form of the hormone progesterone, commonly used to treat various menstrual disorders, including irregular periods and abnormal uterine bleeding. In your girlfriend's case, she has taken Provera 5mg daily for 21 days, which is typically prescribed to help regulate the menstrual cycle.

After completing a course of Provera, most women can expect their menstrual period to start within a week or two. The timing can vary based on individual hormonal balance and the specific reasons for taking the medication. In many cases, menstruation will occur within 3 to 7 days after stopping the medication. However, it’s essential to note that individual responses can differ, and some women may experience a delay.

Regarding side effects, Provera can cause various reactions, although not everyone will experience them. Common side effects include breast tenderness, mood changes, headaches, nausea, and irregular bleeding. Some women may also experience weight gain or changes in their menstrual cycle. It's crucial for your girlfriend to monitor her body’s responses after stopping the medication and report any severe or concerning symptoms to a healthcare provider.

If your girlfriend is experiencing irregular periods or other menstrual issues, it is advisable for her to consult with a gynecologist or healthcare provider. They can conduct a thorough evaluation, including a physical examination and possibly hormonal testing, to determine the underlying cause of her menstrual irregularities. Based on the findings, they can recommend appropriate treatments or lifestyle changes to help regulate her menstrual cycle effectively.

For future menstrual regulation, it’s essential that any medication, including Provera, is taken under the guidance of a healthcare professional. Self-medicating or taking medications without proper medical advice can lead to complications or ineffective treatment. If your girlfriend has a history of irregular periods, her doctor may suggest a tailored treatment plan that could include hormonal therapy, lifestyle modifications, or other interventions based on her specific health needs.

In summary, after completing the 21-day course of Provera, your girlfriend can expect her period to start within a week or two. While there are potential side effects, many women tolerate the medication well. It’s vital for her to seek medical advice for any ongoing menstrual issues and to ensure that any future treatments are appropriately managed by a healthcare professional.

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