Assessing the Toxicity of Household Insecticides on Human Skin - Dermatology

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Toxicity of pesticides on human skin?


I would like to inquire about the toxicity of household insecticides to humans.
I previously purchased "Bayer's Baythroid" cockroach gel, which contains the active ingredient indoxacarb, and it is marketed as having low toxicity to mammals.
The application method involves placing a rice-sized dose on a piece of paper indoors, but I accidentally had some clothing come into contact with the cockroach gel (at that time, the bait had already spread a bit on the paper and seemed somewhat dried).
Afterward, I washed the clothing in the washing machine.
Although I took this action, I am still concerned that some of the gel may have dissolved in the water and spread to other clothes.
I would like to know how toxic diluted indoxacarb is to humans.
Thank you for your response, doctor.

Minzhong, 20~29 year old female. Ask Date: 2010/08/17

Dr. Huang Ruiyun reply Dermatology


Hello: Ivermectin has strong insecticidal properties while exhibiting low toxicity to humans.
This is because insects have a specific receptor in their nervous system that, when exposed to ivermectin, leads to their death, whereas the human nervous system lacks this receptor.
It does not have direct toxicity to human skin, and as long as you do not ingest the cockroach gel, there is no need for concern.
Wishing you peace of mind.

Reply Date: 2010/08/17

More Info


When assessing the toxicity of household insecticides, particularly those containing active ingredients like Indoxacarb (the main component in Bayer's "Bait Pad" cockroach gel), it is essential to understand both the chemical properties of the insecticide and its potential effects on human health. Indoxacarb is designed to target the nervous systems of insects, which is why it is effective against cockroaches. However, it is important to note that its mechanism of action is not harmful to humans, as our nervous systems do not have the same receptors that Indoxacarb targets in insects.

In your situation, where some clothing accidentally came into contact with the insecticide, it is understandable to have concerns about potential toxicity. Indoxacarb is classified as having low toxicity to mammals, which includes humans. The risk of skin absorption from a dry or slightly spread-out gel is minimal, especially if the gel has dried. The primary concern would arise if the insecticide were ingested or if there were prolonged skin contact with a fresh application.

When you washed the clothing, the washing machine would have diluted any residual Indoxacarb present on the fabric. The dilution effect, combined with the washing process, significantly reduces the concentration of the insecticide. While it is theoretically possible for some of the chemical to remain on the clothing, the likelihood of it being at a concentration that poses a health risk is very low. The Environmental Protection Agency (EPA) and other health organizations have established safety guidelines for the use of such products, which include recommendations for proper application and handling to minimize exposure.

In terms of the toxicity of diluted Indoxacarb, studies have shown that even at higher concentrations, the risk to human health is low when proper precautions are taken. The primary route of exposure that poses a risk would be through ingestion or significant dermal exposure to fresh product. Since you have already washed the clothing, the risk of any significant exposure is further minimized.

It is also worth noting that if you experience any unusual symptoms such as skin irritation, respiratory issues, or gastrointestinal distress after potential exposure, it would be prudent to consult a healthcare professional. They can provide guidance based on your specific circumstances and any symptoms you may be experiencing.

In summary, while it is always wise to be cautious when using household insecticides, the specific situation you described—accidental contact with dried gel and subsequent washing—should not pose a significant health risk. Indoxacarb is designed to be low in toxicity to humans, and the washing process would have further diluted any potential residue. Always follow the manufacturer's instructions for use and safety precautions to minimize any risks associated with household insecticides. If you have ongoing concerns, consider reaching out to a medical professional or a poison control center for personalized advice.

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