Becaplermin: Benefits for Diabetic Foot Wounds

Q: Becaplermin: Benefits for Diabetic Foot Wounds

Hello： Due to concerns about carcinogenicity, although the Department of Health had previously approved it, the domestic license holder, Johnson & Johnson, has stopped importing this gel. <br>Wishing you safety.

Becaplermin

I know an elderly person with diabetes who has difficulty healing wounds on their toes (they have had two toes amputated).
I came across a new medication called Bekapamin online, but I'm not sure how effective it is for diabetic patients.
Where can I purchase it, and what is the price? Thank you.

Ping, 40~49 year old female. Ask Date: 2010/08/31

Dr. Huang Ruiyun reply Dermatology

Hello: Due to concerns about carcinogenicity, although the Department of Health had previously approved it, the domestic license holder, Johnson & Johnson, has stopped importing this gel.
Wishing you safety.

Reply Date: 2010/08/31

More Info

Becaplermin, also known as recombinant human platelet-derived growth factor (rhPDGF), is a topical gel that has been approved for the treatment of diabetic foot ulcers. It is particularly indicated for full-thickness diabetic ulcers that are less than or equal to 5 cm² in size. The primary mechanism of action of Becaplermin is to promote wound healing by stimulating cellular processes that are essential for tissue repair, including cell proliferation and the formation of granulation tissue. This is particularly beneficial for diabetic patients, who often experience delayed wound healing due to poor blood circulation, neuropathy, and other complications associated with diabetes.

The benefits of using Becaplermin for diabetic foot wounds include:
1. Enhanced Healing: Clinical studies have shown that Becaplermin can significantly improve the healing rates of diabetic foot ulcers compared to standard care. By promoting the formation of new tissue and blood vessels, it helps to close wounds more effectively.

2. Reduced Risk of Infection: By facilitating faster healing, Becaplermin may help reduce the risk of infections that can complicate diabetic foot wounds. Infections are a major concern for diabetic patients, as they can lead to severe complications, including the need for amputation.

3. Improved Quality of Life: Faster healing of foot wounds can lead to improved mobility and overall quality of life for diabetic patients. This is particularly important for elderly patients or those with limited mobility.

4. Minimal Systemic Absorption: Becaplermin is a topical treatment, which means it is applied directly to the wound site. This minimizes the risk of systemic side effects, making it a safer option for patients who may be taking other medications.

In terms of availability, Becaplermin is a prescription medication, so it is essential to consult with a healthcare provider to obtain it. The healthcare provider will assess the patient's specific condition and determine if Becaplermin is an appropriate treatment option. Once prescribed, it can typically be obtained at pharmacies that carry specialty medications. The cost of Becaplermin can vary significantly depending on the pharmacy and the patient's insurance coverage, but it is generally considered to be on the higher end of the price spectrum for topical treatments.

It is crucial to note that while Becaplermin can be effective, it is not a standalone solution. Proper management of diabetes, including blood sugar control, is vital for wound healing. Patients should also be educated about foot care, including regular inspections of their feet, proper footwear, and prompt treatment of any injuries or wounds.
In summary, Becaplermin offers a promising option for diabetic patients struggling with foot wounds, particularly when used as part of a comprehensive treatment plan that includes good diabetes management and regular medical follow-up. If you or your loved one is considering this treatment, it is advisable to discuss it with a healthcare provider who can provide personalized recommendations based on the individual's health status and needs.

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