Elevated Liver Enzymes: Concerns and Next Steps - Internal Medicine

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SGOT: 22, SGPT: 43


On September 21, my health check report indicated that my GOT is 22 and GPT is 43.
I do not have Hepatitis B or C.
Although my levels are only slightly above the standard values by 3, I am still quite worried.
Today, I visited a traditional Chinese medicine doctor at a large hospital, and he only advised me to go to bed earlier.

1.
If I sleep earlier, will my GPT levels return to normal?
2.
Is my liver inflamed? The Chinese medicine doctor seemed not very concerned after reviewing my health report.
3.
Is it possible to transmit the virus through saliva?
4.
If I go to the hospital, should I see an internist? Will I need to have blood drawn again to check my GPT levels?
5.
I have been experiencing a lot of acne lately and have been taking Western medicine for about six weeks.
Could this be the reason for the increase in my GPT levels?
I apologize for asking so many questions, but I am genuinely quite anxious, especially with an important exam coming up.
Thank you very much.

Qiao, 10~19 year old female. Ask Date: 2010/10/09

Dr. Xiao Jingqin reply Internal Medicine


There are many reasons for elevated liver function tests, with common causes including viral hepatitis, fatty liver disease, alcoholic hepatitis, and drug-induced hepatitis.
Based on your levels, it does not appear to be viral hepatitis (acute hepatitis A or E can likely be ruled out), and even hepatitis A or E is transmitted via the fecal-oral route, not through respiratory droplets.
To check the ACT value, a blood draw is necessary.
You can consult two departments in the hospital: Internal Medicine and Family Medicine.
If you desire more detailed examinations and explanations, you may want to see a Hepatology or Gastroenterology specialist.
If necessary, an abdominal ultrasound may be arranged to rule out fatty liver and other conditions.
The treatment for liver inflammation primarily focuses on removing the underlying cause, such as viral infections, medications, or obesity.
Resting and avoiding overexertion may help lower liver enzyme levels, but the most important factor is addressing the underlying cause.

Reply Date: 2010/10/09

More Info


Elevated liver enzymes, specifically GOT (AST) and GPT (ALT), can be a source of concern for many individuals, especially when they are slightly above the normal range, as in your case. Let's address your questions and provide some context regarding liver health and enzyme levels.

1. Will going to bed early normalize GPT levels?
While getting adequate sleep is essential for overall health and can support liver function, it is unlikely that simply going to bed early will directly lower your GPT levels. Elevated liver enzymes can be indicative of various underlying issues, including inflammation, fatty liver disease, or even the effects of medications. A holistic approach that includes a balanced diet, regular exercise, and avoiding alcohol or hepatotoxic substances is more likely to help normalize liver enzyme levels.

2. Is my liver inflamed?
Elevated GPT levels can suggest liver inflammation, but they do not provide a definitive diagnosis on their own. The degree of elevation, along with other factors such as symptoms, medical history, and additional tests, are necessary to determine if there is indeed inflammation or another liver condition. It’s important to follow up with your healthcare provider for a comprehensive evaluation.

3. Can liver disease be transmitted through saliva?
Hepatitis B and C, the most common viral infections affecting the liver, are primarily transmitted through blood and bodily fluids, not saliva. While Hepatitis B can be found in saliva, the risk of transmission through casual contact (like kissing) is very low. It is essential to practice safe behaviors, especially if you are aware of any potential exposure to these viruses.

4. Should I see an internal medicine specialist?
Yes, if you are concerned about your liver enzyme levels, it would be prudent to consult with an internal medicine physician or a gastroenterologist. They can provide a thorough evaluation, including a physical examination and possibly additional tests such as imaging studies or liver function tests. If you want to monitor your GPT levels, blood tests will be necessary to track any changes over time.

5. Could my recent acne treatment have caused the increase in GPT?
Certain medications, including some used for acne treatment, can lead to elevated liver enzymes as a side effect. If you have been taking any new medications, it is essential to discuss this with your doctor. They may consider whether your current medications could be contributing to the elevation in liver enzymes and whether an alternative treatment might be more suitable.

In summary, while your elevated liver enzymes are a valid concern, they are not necessarily indicative of a severe problem, especially if they are only slightly elevated. It is crucial to approach this situation with a comprehensive plan that includes lifestyle modifications, regular monitoring, and professional medical advice. If you experience any new symptoms, such as jaundice (yellowing of the skin or eyes), abdominal pain, or unusual fatigue, seek medical attention promptly. Remember, managing stress, especially with upcoming exams, is also vital for your overall health.

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