Prostate Issues: Common Concerns and Questions Answered - Urology

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Prostate issues, seeking advice again!


Dear Dr.
Hsu,
First of all, I am very grateful for your thoughtful response amidst your busy schedule! As you mentioned, my previous doctor also stated that a bladder puncture should not cause any sexual dysfunction and should not affect urination.
However, why has my semen disappeared? Although I no longer need it, I am curious about why this condition has occurred.
Additionally, I noticed in my medical records from the ultrasound report that the doctor noted: "no abnormalities, some calcification." Is this what you referred to as "fibrosis"? What symptoms can "fibrosis" cause, and what consequences might it have?
Regarding urodynamics, I had an examination a few years ago, and the doctor said there were no significant issues.
However, in the past six months, my urine output has decreased, and I have experienced intermittent urination.
What does this indicate? Furthermore, you mentioned that "PSA levels fluctuate, mostly indicating inflammation," which is why I have undergone two courses of antibiotics in the past, but my symptoms seem to have shown little improvement.
This fluctuating PSA level has been observed over the past five years.
I have consulted three teaching hospitals and one medical center in Taipei, and I have tried various medications for the prostate (such as Tamsulosin, HARnalidge, Baclospas, Xatral, Urotrol, Urnal, Detrusitol, Borymycin, Ciproxin, Avodart, etc.).
Each time, the doctors have provided vague explanations without definitive answers.
I have taken Avodart, and my prostate has shrunk by one-third, yet my frequent urination persists.

Additionally, is there a correlation between benign prostatic hyperplasia and overactive bladder? Could the bladder capacity be reduced? As a patient you do not know, I sincerely appreciate your response! Thank you once again!
A citizen troubled by prostate issues.

A common citizen troubled by prostate issues., 50~59 year old female. Ask Date: 2010/10/26

Dr. Xu Weikai reply Urology


Hello, the absence of semen may be due to aging or blockage of the ejaculatory duct after a biopsy, and fibrosis simply describes a phenomenon, similar to how skin heals and forms a scar; clinically, this can be referred to as fibrosis.
Additionally, in the case of prostate cancer, PSA levels typically do not decrease; they rarely drop to the normal range.
Therefore, if PSA levels can be brought to normal through treatment, the likelihood of cancer is very low.
Furthermore, if there are urinary difficulties, a urodynamic study may be considered to clearly identify the cause.
If there are any unclear points, feel free to ask again for further discussion and research.
This message is from Dr.
Hsu Wei-Kai, Director of Urology, Taitung Hospital, Department of Health, Executive Yuan, Taiwan.

Reply Date: 2010/10/26

More Info


Understanding prostate issues can be quite complex, especially when symptoms persist despite various treatments. Your concerns about the loss of semen, the presence of calcifications, and fluctuating PSA levels are valid and warrant a thorough discussion.

Firstly, regarding the absence of semen, this condition is known as "dry orgasm." It can occur due to several reasons, including prostate surgery, certain medications, or nerve damage. While your previous doctor indicated that a bladder puncture would not affect sexual function, it is possible that the procedure or the underlying condition may have impacted the seminal vesicles or the prostate itself, leading to this change. It’s important to discuss this with your healthcare provider to explore potential causes and management options.

The calcifications noted in your ultrasound report could indeed be related to a phenomenon known as "fibrosis." Fibrosis in the prostate can occur due to chronic inflammation or infection, leading to scarring. Symptoms of fibrosis may not be overt; however, it can contribute to urinary issues such as difficulty urinating, decreased flow rate, and even discomfort. Over time, significant fibrosis could potentially lead to complications like urinary retention or recurrent urinary tract infections.

You mentioned experiencing a decrease in urine volume and intermittent flow over the past six months. These changes could indicate a progression of benign prostatic hyperplasia (BPH) or bladder dysfunction. BPH can lead to bladder outlet obstruction, which may cause the bladder to become less efficient over time, resulting in a reduced capacity and increased urgency or frequency of urination. It’s essential to monitor these symptoms closely, as they can significantly impact your quality of life.

The fluctuations in your PSA levels are also noteworthy. PSA (Prostate-Specific Antigen) is a protein produced by both normal and malignant cells of the prostate gland. Elevated PSA levels can indicate inflammation, infection, or prostate enlargement, but they are not definitive for cancer. Since you have undergone multiple courses of antibiotics without significant improvement, it may be worthwhile to consider other underlying conditions or to seek a second opinion regarding your treatment plan.

Regarding the relationship between BPH and overactive bladder (OAB), there is indeed a connection. BPH can lead to bladder overactivity due to increased pressure on the bladder neck or due to changes in bladder function. This can result in symptoms such as urgency, frequency, and nocturia (waking at night to urinate). If the bladder's capacity is reduced, it can exacerbate these symptoms.

As for your experience with various medications, it’s not uncommon for patients to try multiple treatments before finding one that effectively manages their symptoms. Medications like Tamsulosin and Avodart are often prescribed to alleviate urinary symptoms associated with BPH, but they may not work for everyone. If you have not seen improvement, discussing alternative therapies or even surgical options with your urologist may be beneficial.

In conclusion, managing prostate issues often requires a multifaceted approach. Regular follow-ups with your healthcare provider, open communication about your symptoms, and possibly exploring new treatment avenues are crucial steps in addressing your concerns. It’s important to advocate for yourself and seek clarity on your condition, especially when symptoms persist despite treatment. Thank you for sharing your experiences, and I hope this information provides some clarity and direction for your ongoing management.

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